What can we learn from the construction of in vitro replication systems?

N Ichihashi - Annals of the New York Academy of Sciences, 2019 - Wiley Online Library
Replication is a central function of living organisms. Several types of replication systems
have been constructed in vitro from various molecules, including peptides, DNA, RNA, and …

Designing minimalist membrane proteins

P Curnow - Biochemical Society Transactions, 2019 - portlandpress.com
The construction of artificial membrane proteins from first principles is of fundamental
interest and holds considerable promise for new biotechnologies. This review considers the …

A fusion method to develop an expanded artificial genomic RNA replicable by Qβ replicase

K Ueda, R Mizuuchi, F Matsuda, N Ichihashi - ChemBioChem, 2019 - Wiley Online Library
RNA‐based genomes are used to synthesize artificial cells that harbor genome replication
systems. Previously, continuous replication of an artificial genomic RNA that encoded an …