Beyond the green fluorescent protein: biomolecular reporters for anaerobic and deep-tissue imaging

HF Ozbakir, NT Anderson, KC Fan… - Bioconjugate …, 2019 - ACS Publications
Fluorescence imaging represents cornerstone technology for studying biological function at
the cellular and molecular levels. The technology's centerpiece is a prolific collection of …

[HTML][HTML] VEGAS as a platform for facile directed evolution in mammalian cells

JG English, RHJ Olsen, K Lansu, M Patel, K White… - Cell, 2019 - cell.com
Directed evolution, artificial selection toward designed objectives, is routinely used to
develop new molecular tools and therapeutics. Successful directed molecular evolution …

Possible magneto-mechanical and magneto-thermal mechanisms of ion channel activation in magnetogenetics

M Barbic - Elife, 2019 - elifesciences.org
The palette of tools for perturbation of neural activity is continually expanding. On the
forefront of this expansion is magnetogenetics, where ion channels are genetically …

Electromagnetic regulation of cell activity

SA Stanley, JM Friedman - Cold Spring …, 2019 - perspectivesinmedicine.cshlp.org
The ability to observe the effects of rapidly and reversibly regulating cell activity in targeted
cell populations has provided numerous physiologic insights. Over the last decade, a wide …

Synthetic biology of yeast

Z Liu, Y Zhang, J Nielsen - Biochemistry, 2019 - ACS Publications
With the rapid development of DNA synthesis and next-generation sequencing, synthetic
biology that aims to standardize, modularize, and innovate cellular functions, has achieved …

Iron-sequestering nanocompartments as multiplexed electron microscopy gene reporters

F Sigmund, S Pettinger, M Kube, F Schneider… - ACS …, 2019 - ACS Publications
Multicolored gene reporters for light microscopy are indispensable for biomedical research,
but equivalent genetic tools for electron microscopy (EM) are still rare despite the increasing …

Engineering a genetically encoded magnetic protein crystal

TL Li, Z Wang, H You, Q Ong, VJ Varanasi, M Dong… - Nano …, 2019 - ACS Publications
Magnetogenetics is a new field that leverages genetically encoded proteins and protein
assemblies that are sensitive to magnetic fields to study and manipulate cell behavior …

Possible magneto-mechanical and magneto-thermal mechanisms of ion channel activation by iron-loaded ferritin in magnetogenetics

M Barbic - bioRxiv, 2019 - biorxiv.org
The palette of tools for stimulation and regulation of neural activity is continually expanding.
One of the new methods being introduced is magnetogenetics, where mechano-sensitive …

Proteins, Polymers and Nanoparticles: Self-assembly Towards Functional Nanostructures

S Manuguri - 2019 - researchspace.auckland.ac.nz
Self-assembly is a fundamental phenomenon that drives every form of life. In the materials
research world, the concept of self-assembly has been applied to synthesize or organize …