The role of personalized atrial modeling in understanding atrial fibrillation mechanisms and improving treatment

KN Aronis, R Ali, NA Trayanova - International journal of cardiology, 2019 - Elsevier
Atrial fibrillation is the most common arrhythmia in humans and is associated with high
morbidity, mortality and health-related expenses. Computational approaches have been …

[HTML][HTML] Understanding AF mechanisms through computational modelling and simulations

KN Aronis, RL Ali, JA Liang, S Zhou… - Arrhythmia & …, 2019 - ncbi.nlm.nih.gov
AF is a progressive disease of the atria, involving complex mechanisms related to its
initiation, maintenance and progression. Computational modelling provides a framework for …

Analysis of a coupled fluid‐structure interaction model of the left atrium and mitral valve

L Feng, H Gao, B Griffith, S Niederer… - International journal for …, 2019 - Wiley Online Library
We present a coupled left atrium‐mitral valve model based on computed tomography scans
with fibre‐reinforced hyperelastic materials. Fluid‐structure interaction is realised by using …

Extent and spatial distribution of left atrial arrhythmogenic sites, late gadolinium enhancement at magnetic resonance imaging, and low-voltage areas in patients with …

J Chen, T Arentz, H Cochet, B Müller-Edenborn… - EP …, 2019 - academic.oup.com
Aims Atrial fibrosis contributes to arrhythmogenesis in atrial fibrillation and can be detected
by MRI or electrophysiological mapping. The current study compares the spatial correlation …

Automatic 3D atrial segmentation from GE-MRIs using volumetric fully convolutional networks

Q Xia, Y Yao, Z Hu, A Hao - … Atlases and Computational Models of the …, 2019 - Springer
In this paper, we propose an approach for automatic 3D atrial segmentation from
Gadolinium-enhanced MRIs based on volumetric fully convolutional networks. The entire …

Dilated convolutions in neural networks for left atrial segmentation in 3D gadolinium enhanced-MRI

S Vesal, N Ravikumar, A Maier - … Atlases and Computational Models of the …, 2019 - Springer
Segmentation of the left atrial chamber and assessing its morphology, are essential for
improving our understanding of atrial fibrillation, the most common type of cardiac …

Arrhythmogenic propensity of the fibrotic substrate after atrial fibrillation ablation: a longitudinal study using magnetic resonance imaging-based atrial models

RL Ali, JB Hakim, PM Boyle, S Zahid… - Cardiovascular …, 2019 - academic.oup.com
Aims Inadequate modification of the atrial fibrotic substrate necessary to sustain re-entrant
drivers (RDs) may explain atrial fibrillation (AF) recurrence following failed pulmonary vein …

[HTML][HTML] A technique for measuring anisotropy in atrial conduction to estimate conduction velocity and atrial fibre direction

CH Roney, J Whitaker, I Sim, L O'Neill… - Computers in biology …, 2019 - Elsevier
Background Cardiac conduction properties exhibit large variability, and affect patient-
specific arrhythmia mechanisms. However, it is challenging to clinically measure conduction …

In vivo ratiometric optical mapping enables high-resolution cardiac electrophysiology in pig models

P Lee, JG Quintanilla… - Cardiovascular …, 2019 - academic.oup.com
Aims Cardiac optical mapping is the gold standard for measuring complex electrophysiology
in ex vivo heart preparations. However, new methods for optical mapping in vivo have been …

Attention based hierarchical aggregation network for 3D left atrial segmentation

C Li, Q Tong, X Liao, W Si, Y Sun, Q Wang… - Statistical Atlases and …, 2019 - Springer
Atrial fibrillation (AF) is the most common type of cardiac arrhythmia. The atrial segmentation
is essential for the understanding of the human atria structure which is vital to the AF …