GABRB3 is highly expressed early in the developing brain, and its encoded β3 subunit is
critical for GABAA receptor assembly and trafficking as well as stem cell differentiation in …

Abstract Background Mutations in SLC6A1 have been associated mainly with myoclonic
atonic epilepsy (MAE) and intellectual disability. We identified a novel missense mutation in …

Vascular endothelial cell damage is related to many vascular diseases, including
cardiovascular disease (CVD). Reactive oxygen species (ROS) play a vital role in the …

Dendritic cells (DCs) are regarded as the gatekeepers of the immune system but can also
mediate systemic dissemination of the obligate intracellular parasite Toxoplasma gondii …

Background Acute liver failure (ALF) from severe acute liver injury is a critical condition
associated with high mortality. The purpose of this study was to investigate the impact of …

GABRR1 is a rho subunit receptor of GABA, the major inhibitory neurotransmitter in the
mammalian brain. While most investigations of its function focused on the nervous system …

Gamma-amino butyric acid (GABA) is the main inhibitory neurotransmitter in the central
nervous system, including the retina, and play an important role in both regulating …

Background/Aim: Several links between DNA replication, pluripotency and development
have been recently identified. The involvement of miRNA in the regulation of cell cycle …

We showed recently that ethyl-2-amino-pyrrole-3-carboxylates (EAPCs) exhibit potent
antiproliferative activities against a broad spectrum of soft tissue sarcoma and …

多巴胺缺乏雖然是目前帕金森氏症治療研究的目標物, 但多巴胺並非唯一受帕金森氏症影響的
神經傳導物質, 這種疾病也會擾亂其他大腦化學物質, 像是血清素, 正腎上腺素和乙醯膽鹼 …