[HTML][HTML] Overexpression of microRNA-21 mediates Ang II-induced renal fibrosis by activating the TGF-β1/Smad3 pathway via suppressing PPARα

H Lyu, X Li, Q Wu, L Hao - Journal of Pharmacological Sciences, 2019 - Elsevier
Abstract Angiotensin II (Ang II) is an important profibrotic factor, and the tumor-promoting
microRNA miR-21 was recently linked to fibrotic disorders. We aimed to investigate whether …

Glomerular hyperfiltration: an early marker of nephropathy in Fabry disease

E Riccio, M Sabbatini, D Bruzzese… - Nephron, 2019 - karger.com
Background and objectives: Progressive nephropathy is one of the main features of Fabry
disease (FD). It has been supposed that an early phase, clinically silent disease occurs in …

Angiotensin receptor neprilysin inhibition for the treatment of hypertension: the neglected child in cardiovascular pharmacotherapy

SE Kjeldsen, D Atar… - European Heart Journal …, 2019 - academic.oup.com
The potential of novel expensive drugs to capture relevant shares in markets saturated with
affordable effective pharmacological agents will, understandably always be a concern for …

[PDF][PDF] Programa de Doctorado en Biomedicina y Farmacia

TOP HYPERCHOLESTEROLEMIA, AC SÁNCHEZ - roderic.uv.es
•“Estudio de los mecanismos moleculares y celulares en la disfunción endotelial asociada a
enfermedades con inflamación sistémica que podrían inducir desórdenes …

Mast cell inhibition in diseases of the retina and vitreous

RB Silver, N O'connor - US Patent 10,517,839, 2019 - Google Patents
VLARUOGDXDTHEH-UHFFFAOYSA-L O= C1C= C (C (= O) O [Na]) OC2= CC= CC (OCC
(O) COC3= CC= CC4= C3C (= O) C= C (C (= O) O [Na]) O4)= C12 Chemical compound O …