Cisplatin and beyond: molecular mechanisms of action and drug resistance development in cancer chemotherapy

T Makovec - Radiology and oncology, 2019 - sciendo.com
Background. Platinum-based anticancer drugs are widely used in the chemotherapy of
human neoplasms. The major obstacle for the clinical use of this class of drugs is the …

Nanocarrier-based systems for targeted and site specific therapeutic delivery

J Majumder, O Taratula, T Minko - Advanced drug delivery reviews, 2019 - Elsevier
Systemic drug delivery methods such as oral or parenteral administration of free drugs
possess relatively low treatment efficiency and marked adverse side effects. The use of …

Long-term drug delivery using implantable electrospun woven polymeric nanotextiles

S Padmakumar, B Paul-Prasanth, K Pavithran… - … , Biology and Medicine, 2019 - Elsevier
A woven nanotextile implant was developed and optimized for long-term continuous drug
delivery for potential oncological applications. Electrospun polydioxanone (PDS) nanoyarns …

High Pressure Nebulization (PIPAC) Versus Injection for the Intraperitoneal Administration of mRNA Complexes

M Shariati, H Zhang, L Van de Sande… - Pharmaceutical …, 2019 - Springer
Purpose Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a novel technique
delivering drugs into the abdominal cavity as an aerosol under high pressure. It is …

Genetic and epigenetic strategies for advancing ovarian cancer immunotherapy

Y Cho, L Milane, MM Amiji - Expert Opinion on Biological Therapy, 2019 - Taylor & Francis
Introduction: Immuno-oncology is currently the most popular field of cancer research and
development. The surge of interest in immuno-oncology stems from recent clinical approvals …

Backbone resonance assignment of human DJ-1 in the reduced state and in the cysteine sulfinic acid state

L Barbieri, E Luchinat - Biomolecular NMR Assignments, 2019 - Springer
DJ-1 is a highly conserved soluble protein that is associated to several cellular pathways. In
humans, DJ-1 has been implicated in several pathologies such as cancer, Parkinson's …