Precision medicine is a patient-specific approach that integrates all relevant clinical, genetic
and biological information in order to optimise the therapeutic benefit relative to the …

Update on the Pathogenesis of Chronic Obstructive Pulmonary Disease | New England Journal of
Medicine Skip to main content The New England Journal of Medicine homepage Advanced …

Transcription factor nuclear factor erythroid 2‐related factor 2 (Nrf2) is a major regulator of
antioxidant response element‐(ARE‐) driven cytoprotective protein expression. The …

Rationale: Evidence suggests damage to small airways is a key pathologic lesion in chronic
obstructive pulmonary disease (COPD). Computed tomography densitometry has been …

Chronic airflow limitation is the common denominator of patients with chronic obstructive
pulmonary disease (COPD). However, it is not possible to predict morbidity and mortality of …

Background: The objective of this study was to compare fatigue levels between subjects with
and without COPD, and to investigate the relationship between fatigue, demographics …

Background COPD is a highly heterogeneous disease composed of different phenotypes
with different aetiological and prognostic profiles and current classification systems do not …

Although they are known to share pathophysiological processes, the relationship between
periodontitis and chronic obstructive pulmonary disease (COPD) is not fully understood. The …

Rationale: Cor pulmonale (right ventricular [RV] dilation) and cor pulmonale parvus (RV
shrinkage) are both described in chronic obstructive pulmonary disease (COPD). The …

Background Chronic obstructive pulmonary disease (COPD) has been recognised as a
global health concern, and one of the leading causes of morbidity and mortality worldwide …