Pharmacological manipulation of the circadian clock: a possible approach to the management of bipolar disorder

A Porcu, R Gonzalez, MJ McCarthy - CNS drugs, 2019 - Springer
Bipolar disorder (BD) is a mood disorder with genetic and neurobiological underpinnings,
characterized primarily by recurrent episodes of mania and depression, with notable …

Dosage sensitivity intolerance of VIPR2 microduplication is disease causative to manifest schizophrenia-like phenotypes in a novel BAC transgenic mouse model

X Tian, A Richard, MW El-Saadi, A Bhandari… - Molecular …, 2019 - nature.com
Recent genome-wide association studies (GWAS) have identified copy number variations
(CNVs) at chromosomal locus 7q36. 3 that significantly contribute to the risk of …

Genome-wide effects of social status on DNA methylation in the brain of a cichlid fish, Astatotilapia burtoni

AT Hilliard, D Xie, Z Ma, MP Snyder, RD Fernald - BMC genomics, 2019 - Springer
Background Successful social behavior requires real-time integration of information about
the environment, internal physiology, and past experience. The molecular substrates of this …

Decreased Expression of Synaptophysin 1 (SYP1 Major Synaptic Vesicle Protein p38) and Contactin 6 (CNTN6/NB3) in the Cerebellar Vermis of reln Haplodeficient …

C Castagna, A Merighi, L Lossi - Cellular and Molecular Neurobiology, 2019 - Springer
Abstract Reeler heterozygous mice (reln+/−) are seemingly normal but haplodeficient in reln,
a gene implicated in autism. Structural/neurochemical alterations in the reln+/− brain are …