Novel approaches for the development of live attenuated influenza vaccines

P Blanco-Lobo, A Nogales, L Rodríguez… - Viruses, 2019 - mdpi.com
Influenza virus still represents a considerable threat to global public health, despite the
advances in the development and wide use of influenza vaccines. Vaccination with …

Generation of DelNS1 influenza viruses: a strategy for optimizing live attenuated influenza vaccines

P Wang, M Zheng, SY Lau, P Chen, BWY Mok, S Liu… - MBio, 2019 - Am Soc Microbiol
ABSTRACT Nonstructural protein 1 (NS1) of influenza virus is a key virulence element with
multifunctional roles in virus replication and a potent antagonist of host immune response …

octoFLU: automated classification for the evolutionary origin of influenza A virus gene sequences detected in US Swine

J Chang, TK Anderson, MA Zeller… - Microbiology …, 2019 - Am Soc Microbiol
The diversity of the 8 genes of influenza A viruses (IAV) in swine reflects introductions from
nonswine hosts and subsequent antigenic drift and shift. Here, we curated a data set and …

[HTML][HTML] Design and characterization of a consensus hemagglutinin vaccine immunogen against H3 influenza A viruses of swine

H Sun, JH Sur, S Sillman, D Steffen, HLX Vu - Veterinary microbiology, 2019 - Elsevier
The substantial genetic diversity exhibited by influenza A viruses of swine (IAV-S) represents
the main challenge for the development of a broadly protective vaccine against this …

Double-attenuated influenza virus elicits broad protection against challenge viruses with different serotypes in swine

S Mamerow, R Scheffter, S Röhrs, O Stech… - Veterinary …, 2019 - Elsevier
Influenza A viruses (IAV) have caused seasonal epidemics and severe pandemics in
humans. Novel pandemic strains as in 2009 may emerge from pigs, serving as perpetual …

[PDF][PDF] Vaccines against equine influenza

LV Kostina, TV Grebennikova… - BIOLOGY …, 2019 - agrobiology.ru
A bstract Equine influenza is a highly infectious disease that can rapidly spread and induce
high morbidity in susceptible horse populations (KP Yurov, 2009; SP Waghmare et al …

ВАКЦИНЫ ПРОТИВ ГРИППА ЛОШАДЕЙ

ЛВ Костина, ТВ Гребенникова… - …, 2019 - cyberleninka.ru
Грипп лошадей-высокоинфекционное заболевание, характеризующееся тенденцией к
быстрому распространению и высокой заболеваемостью среди чувствительного …

Compositions and methods for vaccination against influenza A virus

V Huber, Y Fang - US Patent 10,376,574, 2019 - Google Patents
Disclosed herein are compositions and methods useful for immunizing a subject against
disease caused by influenza A. Disclosed methods comprise administering to the subject an …

Animal influenza viruses-Impacts of influenza A virus in Danish swine herds

P Ryt-Hansen - 2019 - orbit.dtu.dk
Since the filtration experiments performed by Richard E. Shope in 1931, swine influenza A
virus (swIAV) has been linked to influenza-like symptoms in pigs, including fever, coughing …