Lipid assemblies at the crossroads of aging, proteostasis, and neurodegeneration
N Roitenberg, E Cohen - Trends in Cell Biology, 2019 - cell.com
The proteostasis network (PN) is a nexus of mechanisms that act in concert to maintain the
integrity of the proteome. Efficiency of the PN declines with age, resulting in the …
integrity of the proteome. Efficiency of the PN declines with age, resulting in the …
Mechanisms of aggresome biogenesis: ubiquitination, transport, & maintenance
AJ Keefe - 2019 - preprints.org
Neurodegenerative diseases are universally marked by the accumulation of misfolded
protein. Neurons respond to these proteostatic disturbances by sequestering, and thus …
protein. Neurons respond to these proteostatic disturbances by sequestering, and thus …