Reaching an evidence-based prognosis for personalized treatment of multiple sclerosis
D Rotstein, X Montalban - Nature Reviews Neurology, 2019 - nature.com
Personalized treatment is ideal for multiple sclerosis (MS) owing to the heterogeneity of
clinical features, but current knowledge gaps, including validation of biomarkers and …
clinical features, but current knowledge gaps, including validation of biomarkers and …
Mitochondrial dysfunction and multiple sclerosis
IP Barcelos, RM Troxell, JS Graves - Biology, 2019 - mdpi.com
In recent years, several studies have examined the potential associations between
mitochondrial dysfunction and neurodegenerative diseases such as multiple sclerosis (MS) …
mitochondrial dysfunction and neurodegenerative diseases such as multiple sclerosis (MS) …
The interaction between viral and environmental risk factors in the pathogenesis of multiple sclerosis
RE Tarlinton, T Khaibullin, E Granatov… - International journal of …, 2019 - mdpi.com
Multiple sclerosis (MS) is a chronic debilitating inflammatory disease of unknown ethology
targeting the central nervous system (CNS). MS has a polysymptomatic onset and is usually …
targeting the central nervous system (CNS). MS has a polysymptomatic onset and is usually …
The role of glial–neuronal metabolic cooperation in modulating progression of multiple sclerosis and neuropathic pain
RR Robinson, AK Dietz, AM Maroof, R Asmis… - …, 2019 - Taylor & Francis
While the etiology of multiple sclerosis (MS) remains unclear, research from the clinic and
preclinical models identified the essential role of inflammation and demyelination in the …
preclinical models identified the essential role of inflammation and demyelination in the …
Genetic differences between primary progressive and relapsing-remitting multiple sclerosis: The impact of immune-related genes variability
I Kiselev, V Bashinskaya, N Baulina, M Kozin… - Multiple sclerosis and …, 2019 - Elsevier
Background Multiple sclerosis (MS) is a chronic autoimmune disease of CNS with a highly
heterogeneous clinical course. The role of the genetic variability in determination of MS …
heterogeneous clinical course. The role of the genetic variability in determination of MS …
Anti‐inflammatory disease‐modifying treatment and disability progression in primary progressive multiple sclerosis: a cohort study
Background and purpose Treatment options in primary progressive multiple sclerosis
(PPMS) are scarce and, with the exception of ocrelizumab, anti‐inflammatory agents have …
(PPMS) are scarce and, with the exception of ocrelizumab, anti‐inflammatory agents have …
Clinical trials in multiple sclerosis: potential future trial designs
N Manouchehri, Y Zhang, A Salter… - Therapeutic …, 2019 - journals.sagepub.com
Clinical trials of new treatments in multiple sclerosis (MS) currently require large sample
sizes and long durations in order to yield reliable results. The differential responses of an …
sizes and long durations in order to yield reliable results. The differential responses of an …
Plasticity in Standard and Maximum Aerobic Metabolic Rates in Two Populations of an Estuarine Dependent Teleost, Spotted Seatrout (Cynoscion nebulosus)
J Song, RW Brill, JR McDowell - Biology, 2019 - mdpi.com
We studied the effects of metabolic cold adaptation (MCA) in two populations of a
eurythermal species, spotted seatrout (Cynoscion nebulosus) along the US East Coast. Fish …
eurythermal species, spotted seatrout (Cynoscion nebulosus) along the US East Coast. Fish …
[HTML][HTML] Progressive onset multiple sclerosis: demographic, clinical and laboratory characteristics of patients with and without relapses in the course
B Kaymakamzade, AK Kiliç, AT Kurne… - Archives of …, 2019 - ncbi.nlm.nih.gov
Amaç Primer progresif multipl skleroz (PPMS) ve progresif relapsing multipl skleroz (PRMS)
başlangıçtan beri olan progresyon ile karakterize MS tipleridir. Nadir görülmelerinden …
başlangıçtan beri olan progresyon ile karakterize MS tipleridir. Nadir görülmelerinden …
Variability of the MIR196A2 Gene as a Risk Factor in Primary-Progressive Multiple Sclerosis Development
IS Kiselev, OG Kulakova, NM Baulina… - Molecular Biology, 2019 - Springer
Multiple sclerosis is a chronic disease of the central nervous system, combining in its
pathogenesis both autoimmune and neurodegenerative components, and is characterized …
pathogenesis both autoimmune and neurodegenerative components, and is characterized …