Duchenne muscular dystrophy (DMD) is an X-linked disorder characterized by progressive
muscle degeneration, caused by the absence of dystrophin. Exon skipping by antisense …

Bone metastasis, a clinical complication of patients with advanced breast cancer, seriously
reduces the quality of life. To avoid destruction of the bone matrix, current treatments focus …

The field of mitochondrial ion channels has undergone a rapid development during the last
three decades, due to the molecular identification of some of the channels residing in the …

It is extremely difficult for cancer chemotherapy to control the peritoneal metastasis of
advanced ovarian carcinoma given its inability to target disseminated tumors and the severe …

Duchenne muscular dystrophy (DMD) is an X-linked recessive fatal neuromuscular disorder
characterized by progressive muscle degeneration which affects one in 3500-5000 males …

A special symposium of the Academy of Pharmaceutical Sciences Nanomedicines Focus
Group reviewed the current status of the use of nanomedicines for the delivery of biologics …

Medulloblastoma is a malignant brain tumor diagnosed in children. Chemotherapy has
improved survival rates to approximately 70%; however, children are often left with long-term …

Paclitaxel (PTX) is a microtubule-stabilizing agent widely used to treat breast cancer.
Nevertheless, the low solubility of the drug and the side effects of commercial formulations …

Cell-penetrating peptides (CPP) are broadly recognized as efficient non-viral vectors for the
internalization of compounds such as peptides, oligonucleotides or proteins. Characterizing …

Polymer-stabilized phospholipid nanodiscs are nanoscale, discoidal assemblies containing
a central core of lipid bilayer stabilized in aqueous solution by an amphipathic copolymer …