Mass spectrometry imaging and its application in pharmaceutical research and development: A concise review
JG Swales, G Hamm, MR Clench… - International Journal of …, 2019 - Elsevier
Understanding the biodistribution, metabolism and accumulation of drugs in the body is a
fundamental of pharmaceutical research and development. Mass Spectrometry imaging …
fundamental of pharmaceutical research and development. Mass Spectrometry imaging …
Imaging of protein distribution in tissues using mass spectrometry: An interdisciplinary challenge
The recent development of mass spectrometry imaging (MSI) technology allowed to obtain
extremely detailed images of the spatial distribution of proteins in tissue at high spatial …
extremely detailed images of the spatial distribution of proteins in tissue at high spatial …
Lipid coverage in nanospray desorption electrospray ionization mass spectrometry imaging of mouse lung tissues
Lipids are a naturally occurring group of molecules that not only contribute to the structural
integrity of the lung preventing alveolar collapse but also play important roles in the anti …
integrity of the lung preventing alveolar collapse but also play important roles in the anti …
Mass spectrometry imaging of brain cholesterol and metabolites with trifluoroacetic acid-enhanced desorption electrospray ionization
X Wang, Y Hou, Z Hou, W Xiong, G Huang - Analytical chemistry, 2019 - ACS Publications
Imaging of cholesterol and other metabolites simultaneously by ambient mass spectrometry
will greatly benefit biological studies, however, it still remains challenging. Herein, by adding …
will greatly benefit biological studies, however, it still remains challenging. Herein, by adding …
Precision pharmacology: Mass spectrometry imaging and pharmacokinetic drug resistance
M Jove, J Spencer, M Clench, PM Loadman… - Critical reviews in …, 2019 - Elsevier
Failure of systemic cancer treatment can be, at least in part, due to the drug not being
delivered to the tumour at sufficiently high concentration and/or sufficiently homogeneous …
delivered to the tumour at sufficiently high concentration and/or sufficiently homogeneous …
Challenging the heterogeneity of disease presentation in malignant melanoma—impact on patient treatment
A Marcell Szasz, J Malm, M Rezeli, Y Sugihara… - Cell Biology and …, 2019 - Springer
There is an increasing global interest to support research areas that can assist in
understanding disease and improving patient care. The National Cancer Institute (NIH) has …
understanding disease and improving patient care. The National Cancer Institute (NIH) has …
Matrix-assisted ionisation in vacuum mass spectrometry and imaging on a modified quadrupole-quadrupole-time-of-flight mass spectrometer
AJ Harding, J Hough, C Curtis, D Kinsman… - Journal of Spectral …, 2019 - shura.shu.ac.uk
Matrix-Assisted Ionisation in Vacuum (MAIV) is a new ionisation technique which ionises
non-volatile compounds producing electrospray ionisation-like spectra. Its simple, matrix …
non-volatile compounds producing electrospray ionisation-like spectra. Its simple, matrix …
Анализ биологических образцов в современной лабораторной практике (обзор)
ИИ Мирошниченко, ЮЕ Шилов - Разработка и регистрация …, 2019 - pharmjournal.ru
Аннотация Введение. В представленной публикации освещены ключевые моменты
основных этапов разработки методик определения следовых количеств …
основных этапов разработки методик определения следовых количеств …
Разработка и валидация методики количественного определения тадалафила в плазме крови человека
ДС Богданова, ТН Комаров, ИЕ Шохин… - Разработка и …, 2019 - pharmjournal.ru
Аннотация Введение. Тадалафил–лекарственный препарат, используемый для
лечения эректильной дисфункции. Для количественного определения тадалафила в …
лечения эректильной дисфункции. Для количественного определения тадалафила в …
[PDF][PDF] High spectral resolution mass spectrometry imaging of three-dimensional cell culture
LH Tucker - 2019 - core.ac.uk
Abstract Three-dimensional (3D) cell culture combines the simplicity of two-dimensional
(2D) cell culture systems with the complex interplay of factors resembling the multifaceted …
(2D) cell culture systems with the complex interplay of factors resembling the multifaceted …