Other preventive anti-migraine treatments: ACE inhibitors, ARBs, calcium channel blockers, serotonin antagonists, and NMDA receptor antagonists

JC Rau, DW Dodick - Current Treatment Options in Neurology, 2019 - Springer
Purpose of review Migraine causes more years of life lived with disability than almost any
other condition in the world and can significantly impact the lives of individuals with …

Alternatives to opioid analgesia in small animal anesthesia: alpha-2 agonists

A Valverde, AM Skelding - Veterinary Clinics: Small Animal …, 2019 - vetsmall.theclinics.com
Alpha-2 agonists have desirable effects, including sedation, analgesia, and minimum
alveolar concentration (MAC) sparing for inhalational anesthetics, and despite profound …

Intrathecal injection of dexmedetomidine ameliorates chronic neuropathic pain via the modulation of MPK3/ERK1/2 in a mouse model of chronic neuropathic pain

Y Qian, Q Wang, J Jiao, G Wang, Z Gu… - Neurological …, 2019 - Taylor & Francis
Objective: Despite the application of dexmedetomidine (DEX) as a perioperative adjuvant in
local analgesia, the exact analgesic mechanism underpinning chronic neuropathic pain …

The α2A‐adrenoceptor subtype plays a key role in the analgesic and sedative effects of xylazine

T Kitano, T Kobayashi, S Yamaguchi… - Journal of veterinary …, 2019 - Wiley Online Library
Xylazine, the classical α2‐adrenoceptor (α2‐AR) agonist, is still used as an analgesic and
sedative in veterinary medicine, despite its low potency and affinity for α2‐ARs. Previous …

Dexmedetomidine/propofol versus dexmedetomidine/ketamine versus dexmedetomidine as a sole agent for pediatric sedation during MRI

MK Abdellatif, TH Ibrahim - Ain-Shams Journal of …, 2019 - asja.journals.ekb.eg
BackgroundPropofol use in MRI procedures is growing worldwide especially for infants and
children. Propofol causes unintended deep sedation and respiratory depression. The safety …

Dexmedetomidine improves surgical field in cochlear implant surgery: a randomized, double-blind, placebo-controlled trial

N Govil, S Dadu, VP Singh, V Rai… - Anaesthesia, Pain & …, 2019 - apicareonline.com
Objectives: Sympatholytic properties of dexmedetomidine have many advantages to use in
general anesthesia especially in pediatric age group undergoing cochlear implant …

Effect of Epidural Dexmedetomidine on Propofol Requirements in Patients Undergoing Abdominal Surgeries Under General Anaesthesia

KM Veeresh - 2019 - search.proquest.com
Background & Objectives: Dexmedetomidine is an Į2 receptor agonist, effective in providing
sedation when administered intravenously and epidurally. We decided to assess the amount …