Sex differences in the metabolic effects of the renin-angiotensin system

MC White, R Fleeman, AC Arnold - Biology of Sex Differences, 2019 - Springer
Obesity is a global epidemic that greatly increases risk for developing cardiovascular
disease and type II diabetes. Sex differences in the obese phenotype are well established in …

[HTML][HTML] Novel stem cell and gene therapy in diabetic retinopathy, age related macular degeneration, and retinitis pigmentosa

PE Ludwig, SC Freeman, AC Janot - International Journal of Retina and …, 2019 - Springer
Degenerative retinal disease leads to significant visual morbidity worldwide. Diabetic
retinopathy and macular degeneration are leading causes of blindness in the developed …

Egg white–derived antihypertensive peptide IRW (Ile‐Arg‐Trp) reduces blood pressure in spontaneously hypertensive rats via the ACE2/ang (1‐7)/mas receptor Axis

W Liao, H Fan, ST Davidge, J Wu - Molecular nutrition & food …, 2019 - Wiley Online Library
Scope It is found in the previous study that egg‐white‐derived antihypertensive peptide Ile‐
Arg‐Trp (IRW) upregulated angiotensin converting enzyme 2 (ACE2) in spontaneously …

Identification of angiotensin converting enzyme 2 (ACE2) up-regulating peptides from pea protein hydrolysate

W Liao, H Fan, P Liu, J Wu - Journal of Functional Foods, 2019 - Elsevier
Abstract Angiotensin converting enzyme 2 (ACE2) degrades vasoconstricting angiotensin II
(Ang II) into angiotensin (1–7), exerting protective effects in cardiovascular system; thus …

Hypoxic regulation of angiotensin‐converting enzyme 2 and Mas receptor in human CD34+ cells

S Joshi, H Wollenzien, E Leclerc… - Journal of cellular …, 2019 - Wiley Online Library
CD34+ hematopoietic stem/progenitor cells (HSPCs) are vasculogenic and hypoxia is a
strong stimulus for the vasoreparative functions of these cells. Angiotensin‐converting …

Interactive effects of apelin, renin–angiotensin system and nitric oxide in treatment of obesity-induced type 2 diabetes mellitus in male albino rats

MM Sabry, MM Mahmoud, HS Shoukry… - … of physiology and …, 2019 - Taylor & Francis
Apelin and its receptor (APJ) are involved in the regulation of a variety of pathophysiological
processes. We studied the effect of apelin treatment on obesity-induced type 2 diabetes …

The effect of angiotensin 1-7 and losartan on renal ischemic/reperfusion injury in male rats

T Safari, MR Shahraki, S Miri… - Research in …, 2019 - journals.lww.com
Abstract Ischemia/reperfusion (I/R) is a major cause of acute kidney injury. Several studies
have shown that renin angiotensin (Ang) system and activation of Ang II type 1 receptor …

[HTML][HTML] The renin-angiotensin-aldosterone system as a potential target for therapy in patients with calcific aortic stenosis: A literature review

AE Kostyunin, EA Ovcharenko, OL Barbarash - Kardiologiia, 2019 - lib.ossn.ru
Calcific aortic valve stenosis (CAVS) is a serious socio-economic problem in developed
countries because this disease is the most common indication for aortic valve replacement …

[PDF][PDF] Effects of the combination of Herba Epimedii and Semen Plentaginis on the aortic ACE2/Angiotensin-(1-7)/Mas receptor axis and blood pressure in …

H Zhang, Y Liu, L Rao, Y Cen, K Cheng - Int. J. Clin. Exp. Med, 2019 - e-century.us
This study evaluated the effects of Herba Epimedii-Semen Plentaginis (HESP) on blood
pressure and aortic intima media thickness (IMT) in spontaneously hypertensive rats (SHR) …

Ренин-ангиотензин-альдостероновая система как потенциальная мишень для терапии пациентов с кальцинирующим аортальным стенозом: обзор …

АЕ Костюнин, ЕА Овчаренко, ОЛ Барбараш - Кардиология, 2019 - lib.ossn.ru
Аннотация Кальцинирующий аортальный стеноз (КАС) представляет собой серьёзную
социально-экономическую проблему в развитых странах, поскольку является наиболее …