[HTML][HTML] Genetics of attention deficit hyperactivity disorder

SV Faraone, H Larsson - Molecular psychiatry, 2019 - nature.com
Decades of research show that genes play an vital role in the etiology of attention deficit
hyperactivity disorder (ADHD) and its comorbidity with other disorders. Family, twin, and …

Genetic associations between voltage-gated calcium channels and psychiatric disorders

A Andrade, A Brennecke, S Mallat, J Brown… - International journal of …, 2019 - mdpi.com
Psychiatric disorders are mental, behavioral or emotional disorders. These conditions are
prevalent, one in four adults suffer from any type of psychiatric disorders world-wide. It has …

Updated European Consensus Statement on diagnosis and treatment of adult ADHD

JJS Kooij, D Bijlenga, L Salerno, R Jaeschke… - European …, 2019 - cambridge.org
Background Attention-deficit/hyperactivity disorder (ADHD) is among the most common
psychiatric disorders of childhood that often persists into adulthood and old age. Yet ADHD …

The role of GPCRs in bone diseases and dysfunctions

J Luo, P Sun, S Siwko, M Liu, J Xiao - Bone research, 2019 - nature.com
The superfamily of G protein-coupled receptors (GPCRs) contains immense structural and
functional diversity and mediates a myriad of biological processes upon activation by …

[HTML][HTML] Does prenatal stress shape postnatal resilience?–an epigenome-wide study on violence and mental health in humans

F Serpeloni, KM Radtke, T Hecker, J Sill… - Frontiers in …, 2019 - frontiersin.org
Stress during pregnancy widely associates with epigenetic changes and psychiatric
problems during childhood. Animal studies, however, show that under specific postnatal …

Maternal immune activation impairs cognitive flexibility and alters transcription in frontal cortex

DA Amodeo, CY Lai, O Hassan, EA Mukamel… - Neurobiology of …, 2019 - Elsevier
Background Epidemiological studies suggest that the risk of neurodevelopmental disorders
such as autism spectrum disorder (ASD) and schizophrenia is increased by prenatal …

The role of glutamate receptors in attention‐deficit/hyperactivity disorder: From physiology to disease

X Huang, M Wang, Q Zhang, X Chen… - American Journal of …, 2019 - Wiley Online Library
Attention‐deficit hyperactivity disorder (ADHD) is the most common psychiatric disorder in
children and adolescents, which is characterized by behavioral problems such as attention …

Autism‐related behaviors in the cyclooxygenase‐2‐deficient mouse model

CT Wong, I Bestard‐Lorigados… - Genes, Brain and …, 2019 - Wiley Online Library
Prostaglandin E2 (PGE2) is an endogenous lipid molecule involved in normal brain
development. Cyclooxygenase‐2 (COX2) is the main regulator of PGE2 synthesis. Emerging …

Cross-species models of attention-deficit/hyperactivity disorder and autism spectrum disorder: lessons from: CNTNAP2:: ADGRL3:, and: PARK2

E Dalla Vecchia, N Mortimer, VS Palladino… - Psychiatric …, 2019 - journals.lww.com
Animal and cellular models are essential tools for all areas of biological research including
neuroscience. Model systems can also be used to investigate the pathophysiology of …

Modeling and predicting developmental trajectories of neuropsychiatric dimensions associated with copy number variations

N Hiroi, T Yamauchi - International Journal of …, 2019 - academic.oup.com
Copy number variants, such as duplications and hemizygous deletions at chromosomal loci
of up to a few million base pairs, are highly associated with psychiatric disorders …