Abstract Purpose of Review The objectives of this article are to review the major changes in
the staging of head and neck cancers and the rationale for the modifications. Recent …

Objective The aim of this study was to systematically review the literature to determine:(a)
the malignant transformation rate (TR) of oral lichen planus (OLP) and its risk factors;(b) …

Objectives/Hypothesis Literature examining long‐term survival in head and neck squamous
cell carcinoma (HNSCC) with human papillomavirus (HPV) status is lacking. We compare 10 …

Squamous cell carcinoma represents the most common form of head and neck cancer—
comprising approximately 90% of all head and neck malignancies. 1 Squamous cell …

Objectives To develop and validate an algorithm to predict occult nodal metastasis in
clinically node negative oral cavity squamous cell carcinoma (OCSCC) using machine …

Background The eighth international symposium for sentinel node biopsy (SNB) in head and
neck cancer was held in 2018. This consensus conference aimed to deliver current …

The proliferation and metastasis ability of tumors are mediate by the" mutual dialogue"
between cells in the tumor microenvironment (TME). Extracellular vesicles (EVs), mainly …

Background TNM8 staging for oropharyngeal squamous cell carcinomas (OPSCC)
surrogates p16 immunohistochemistry for HPV testing. Patients with p16+ OPSCC may lack …

Radiomics studies require many patients in order to power them, thus patients are often
combined from different institutions and using different imaging protocols. Various studies …

Tumors are composed of heterogeneous phenotypes, each having different sensitivities to
the microenvironment. One microenvironment characteristic–matrix stiffness–helps to …