[HTML][HTML] The role of molecular testing for the indeterminate thyroid FNA

ED Rossi, L Pantanowitz, WC Faquin - Genes, 2019 - mdpi.com
Thyroid nodules are common in the adult population where a majority are benign and only
4.0% to 6.5% are malignant. Fine needle aspiration (FNA) is a key method used in the early …

[HTML][HTML] Analytical and clinical validation of expressed variants and fusions from the whole transcriptome of thyroid FNA samples

TE Angell, LJ Wirth, ME Cabanillas… - Frontiers in …, 2019 - frontiersin.org
Introduction: The Afirma® Xpression Atlas (XA) detects gene variants and fusions in thyroid
nodule FNA samples from a curated panel of 511 genes using whole-transcriptome RNA …

Performance of the Afirma genomic sequencing classifier versus gene expression classifier: an institutional experience

S Wei, C Veloski, P Sharda, H Ehya - Cancer cytopathology, 2019 - Wiley Online Library
Background The use of fine‐needle aspiration (FNA) to triage thyroid nodules has resulted
in a significant reduction in thyroid surgery. However, approximately one‐third of FNA …

Thyroid fine-needle aspiration cytology molecular testing in the USA

NP Ohori - Thyroid FNA Cytology: Differential Diagnoses and …, 2019 - Springer
Each year in the USA, approximately 57,000 thyroid cancer cases are diagnosed, and 2000
patients die from this disease [1]. Compared to other common cancers (eg, lung, pancreas …

The Afirma Gene Sequencing Classifier (GSC) Performs Better in Cytologically Indeterminate Thyroid Nodules Than the Afirma Gene Expression Classifier (GEC)

SA Fish - Clinical Thyroidology, 2019 - liebertpub.com
Background Thyroid nodules are common. While most nodules are benign, approximately 7
to 10% of them of malignant (1). The goal in the evaluation of thyroid nodules is to …