Impact of pregravid obesity on maternal and fetal immunity: Fertile grounds for reprogramming
S Sureshchandra, NE Marshall… - Journal of leukocyte …, 2019 - academic.oup.com
Maternal pregravid obesity results in several adverse health outcomes during pregnancy,
including increased risk of gestational diabetes, preeclampsia, placental abruption, and …
including increased risk of gestational diabetes, preeclampsia, placental abruption, and …
Exercise prevents the adverse effects of maternal obesity on placental vascularization and fetal growth
Key points Maternal exercise improves the metabolic health of maternal mice challenged
with a high‐fat diet. Exercise intervention of obese mothers prevents fetal overgrowth …
with a high‐fat diet. Exercise intervention of obese mothers prevents fetal overgrowth …
Insulin stimulates GLUT4 trafficking to the syncytiotrophoblast basal plasma membrane in the human placenta
Context Placental transport capacity influences fetal glucose supply. The syncytiotrophoblast
is the transporting epithelium in the human placenta, expressing glucose transporters …
is the transporting epithelium in the human placenta, expressing glucose transporters …
Uteroplacental glucose uptake and fetal glucose consumption: a quantitative study in human pregnancies
TM Michelsen, AM Holme, MB Holm… - The Journal of …, 2019 - academic.oup.com
Context Maternal glucose levels and body mass index (BMI) are determinants of fetal
overgrowth, but their relation to fetal glucose consumption is not well characterized in …
overgrowth, but their relation to fetal glucose consumption is not well characterized in …
[HTML][HTML] Pre-pregnancy underweight and obesity are positively associated with small-for-gestational-age infants in a Chinese population
YH Chen, L Li, W Chen, ZB Liu, L Ma, XX Gao, JL He… - Scientific reports, 2019 - nature.com
The association between suboptimal pre-pregnancy body mass index (BMI) and small-for-
gestational-age (SGA) infants is not well defined. We investigated the association between …
gestational-age (SGA) infants is not well defined. We investigated the association between …
[HTML][HTML] Normalizing adiponectin levels in obese pregnant mice prevents adverse metabolic outcomes in offspring
ME Paulsen, FJ Rosario, SR Wesolowski… - The FASEB …, 2019 - ncbi.nlm.nih.gov
Infants of obese mothers have an increased risk of developing obesity, insulin resistance,
and type 2 diabetes. The underlying mechanisms remain elusive, and no effective …
and type 2 diabetes. The underlying mechanisms remain elusive, and no effective …
Analysis of correlations between the placental expression of glucose transporters GLUT-1, GLUT-4 and GLUT-9 and selected maternal and fetal parameters in …
PJ Stanirowski, D Szukiewicz, M Pyzlak… - The Journal of …, 2019 - Taylor & Francis
Purpose: The aim of the study was to analyze the correlations between the expression of
glucose transporters GLUT-1, GLUT-4, and GLUT-9 in human term placenta and selected …
glucose transporters GLUT-1, GLUT-4, and GLUT-9 in human term placenta and selected …
No evidence of attenuation of placental insulin-stimulated Akt phosphorylation and amino acid transport in maternal obesity and gestational diabetes mellitus
M Castillo-Castrejon, T Jansson… - American Journal of …, 2019 - journals.physiology.org
Pregnancies complicated by obesity and/or gestational diabetes (GDM) are associated with
peripheral insulin resistance; however, the insulin responsiveness of the placenta in these …
peripheral insulin resistance; however, the insulin responsiveness of the placenta in these …
Insulin-dependent, glucose transporter 1 mediated glucose uptake and tube formation in the human placental first trimester trophoblast cells
S Basak, S Vilasagaram, K Naidu… - Molecular and Cellular …, 2019 - Springer
During early gestation, hypoxic condition is critically maintained by optimal glucose
metabolism and transporter activities. Glucose is readily available energy nutrient required …
metabolism and transporter activities. Glucose is readily available energy nutrient required …
[HTML][HTML] Maternal diet modulates placental nutrient transporter gene expression in a mouse model of diabetic pregnancy
C Kappen, C Kruger, S Jones, NJ Herion… - PLoS One, 2019 - journals.plos.org
Diabetes in the mother during pregnancy is a risk factor for birth defects and perinatal
complications and can affect long-term health of the offspring through developmental …
complications and can affect long-term health of the offspring through developmental …