Personalized medicine has largely been enabled by the integration of genomic and other
data with electronic health records (EHRs) in the United States and elsewhere. Increased …

Over the past decade, scientists and ethicists began to feel that existing regulations for
oversight of human research did not align well with emerging practices and technologies …

The evidence base supporting genetic and genomic sequence-variant interpretations is
continuously evolving. An inherent consequence is that a variant's clinical significance might …

Efforts are underway to harmonise the return of individual results and incidental findings
from whole genome sequencing (WGS) across research contexts and countries. We …

As genomic science has evolved, so have policy and practice debates about how to
describe and evaluate the ways in which genomic information is treated for individuals …

Whilst the underlying principles of precision medicine are comparable across the globe,
genomic references, health practices, costs and discrimination policies differ in Asian …

Purpose Physicians increasingly receive genomic test results they did not order, which we
term “unsolicited genomic results”(UGRs). We asked physicians how they think such results …

Background Assess process, uptake, validity and resource needs for return of actionable
research findings to biobank participants. Methods Participants were prospectively enrolled …

A 2018 committee report published by the highly respected National Academies of Science,
Engineering, and Medicine (the Report) recommends stripping research participants of …

Background: Genomic analysis may reveal both primary and secondary findings with direct
relevance to the health of probands' biological relatives. Researchers question their …