[HTML][HTML] An updated algorithm recommendation for the management of knee osteoarthritis from the European Society for Clinical and Economic Aspects of …

O Bruyère, G Honvo, N Veronese, NK Arden… - Seminars in arthritis and …, 2019 - Elsevier
Abstract Objectives The European Society for Clinical and Economic Aspects of
Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) sought to revisit the …

Bioactive factors for cartilage repair and regeneration: improving delivery, retention, and activity

JM Patel, KS Saleh, JA Burdick, RL Mauck - Acta Biomaterialia, 2019 - Elsevier
Articular cartilage is a remarkable tissue whose sophisticated composition and architecture
allow it to withstand complex stresses within the joint. Once injured, cartilage lacks the …

2018 update of the EULAR recommendations for the management of hand osteoarthritis

M Kloppenburg, FPB Kroon, FJ Blanco… - Annals of the …, 2019 - ard.bmj.com
Since publication of the European League Against Rheumatism (EULAR) recommendations
for management of hand osteoarthritis (OA) in 2007 new evidence has emerged. The aim …

[HTML][HTML] Safety of topical non-steroidal anti-inflammatory drugs in osteoarthritis: outcomes of a systematic review and meta-analysis

G Honvo, V Leclercq, A Geerinck, T Thomas… - Drugs & aging, 2019 - Springer
Objective We aimed to assess the safety of topical non-steroidal anti-inflammatory drugs
(NSAIDs) in the management of osteoarthritis (OA) in a systematic review and meta-analysis …

Urolithin A targets the PI3K/Akt/NF-κB pathways and prevents IL-1β-induced inflammatory response in human osteoarthritis: in vitro and in vivo studies

X Fu, LF Gong, YF Wu, Z Lin, BJ Jiang, L Wu, KH Yu - Food & Function, 2019 - pubs.rsc.org
Osteoarthritis (OA) is a degenerative joint disease, whose progression is closely related to
the inflammatory environment. Urolithin A (UA), a natural metabolite of a class of compounds …

Современные подходы к терапии остеоартрита с учетом обновленных международных рекомендаций

АМ Лила, ЛИ Алексеева, ЕА Таскина - РМЖ. Медицинское обозрение, 2019 - elibrary.ru
Остеоартрит (ОА)-хроническое прогрессирующее заболевание суставов,
представляющее собой серьезную общемедицинскую и социальную проблему …

Treat-to-target strategy for knee osteoarthritis. International technical expert panel consensus and good clinical practice statements

A Migliore, G Gigliucci, L Alekseeva… - Therapeutic …, 2019 - journals.sagepub.com
Background: In this work, we aimed to establish a clinical target in the management of knee
osteoarthritis (KOA) and to propose good clinical practice (GCP) statements for carrying out …

Clinical assessment and management of foot and ankle osteoarthritis: a review of current evidence and focus on pharmacological treatment

KL Paterson, L Gates - Drugs & aging, 2019 - Springer
Foot and ankle osteoarthritis (OA) is a common and disabling problem that adversely affects
physical function and significantly reduces quality of life. Although the knee was considered …

Inhibition of PI3K/Akt/NF‐κB signaling with leonurine for ameliorating the progression of osteoarthritis: in vitro and in vivo studies

ZC Hu, LF Gong, XB Li, X Fu, JW Xuan… - Journal of Cellular …, 2019 - Wiley Online Library
Osteoarthritis (OA) is characterized as the degeneration and destruction of articular
cartilage. In recent decades, leonurine (LN), the main active component in medical and …

NSAID use among residents in 68 residential aged care facilities 2014 to 2017: An analysis of duration, concomitant medication use, and high‐risk conditions

KE Lind, MZ Raban, A Georgiou… - … and drug safety, 2019 - Wiley Online Library
Purpose People in residential aged care are at increased risk of adverse events from
nonsteroidal anti‐inflammatory drugs (NSAIDs) due to their age and health status, but little is …