[HTML][HTML] Immune and inflammatory cells in thyroid cancer microenvironment

SM Ferrari, P Fallahi, MR Galdiero, I Ruffilli… - International journal of …, 2019 - mdpi.com
A hallmark of cancer is the ability of tumor cells to avoid immune destruction. Activated
immune cells in tumor microenvironment (TME) secrete proinflammatory cytokines and …

[HTML][HTML] The immune landscape of thyroid cancer in the context of immune checkpoint inhibition

G Varricchi, S Loffredo, G Marone, L Modestino… - International journal of …, 2019 - mdpi.com
Immune cells play critical roles in tumor prevention as well as initiation and progression.
However, immune-resistant cancer cells can evade the immune system and proceed to form …

[HTML][HTML] Development of a prognostic index based on an immunogenomic landscape analysis of papillary thyroid cancer

P Lin, Y Guo, L Shi, X Li, H Yang, Y He, Q Li… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Background: Papillary thyroid cancer (PTC) is the most common subtype of thyroid cancer,
and inflammation relates significantly to its initiation and prognosis. Systematic exploration …

Papillary thyroid carcinoma behavior: clues in the tumor microenvironment

K Bergdorf, DC Ferguson, M Mehrad… - Endocrine-Related …, 2019 - erc.bioscientifica.com
The prevalence of thyroid carcinoma is increasing and represents the most common
endocrine malignancy, with papillary thyroid carcinoma (PTC) being the most frequent …

[HTML][HTML] Senescent thyrocytes and thyroid tumor cells induce M2-like macrophage polarization of human monocytes via a PGE2-dependent mechanism

M Mazzoni, G Mauro, M Erreni, P Romeo… - Journal of Experimental …, 2019 - Springer
Background Thyroid carcinoma includes several variants characterized by different
biological and clinical features: from indolent microcarcinoma to undifferentiated and …

[HTML][HTML] CD163+ immune cell infiltrates and presence of CD54+ microvessels are prognostic markers for patients with embryonal rhabdomyosarcoma

JN Kather, C Hörner, CA Weis, T Aung, C Vokuhl… - Scientific Reports, 2019 - nature.com
Rhabdomyosarcomas (RMS) are rare and often lethal diseases. It is assumed that the tumor
microenvironment (TME) of RMS exerts an immunosuppressive function, but there is …

Pathways-and epigenetic-based assessment of relative immune infiltration in various types of solid tumors

MD Bacolod, F Barany, K Pilones, PB Fisher… - Advances in Cancer …, 2019 - Elsevier
Recent clinical studies document the power of immunotherapy in treating subsets of patients
with advanced cancers. In this context and with multiple cancer immunotherapeutics already …