Genetics of human female infertility
SA Yatsenko, A Rajkovic - Biology of reproduction, 2019 - academic.oup.com
About 10% of women of reproductive age are unable to conceive or carry a pregnancy to
term. Female factors alone account for at least 35% of all infertility cases and comprise a …
term. Female factors alone account for at least 35% of all infertility cases and comprise a …
Genetic diagnosis of subfertility: the impact of meiosis and maternal effects
During reproductive age, approximately one in seven couples are confronted with fertility
problems. While the aetiology is diverse, including infections, metabolic diseases, hormonal …
problems. While the aetiology is diverse, including infections, metabolic diseases, hormonal …
Serum concentrations of oocyte-secreted factors BMP15 and GDF9 during IVF and in women with reproductive pathologies
AH Riepsamen, K Chan, S Lien, P Sweeten… - …, 2019 - academic.oup.com
Oocyte-secreted factors bone morphogenetic protein 15 (BMP15) and growth differentiation
factor 9 (GDF9) are critical for folliculogenesis and fertility. This study developed ELISAs for …
factor 9 (GDF9) are critical for folliculogenesis and fertility. This study developed ELISAs for …
Regulation of follicle formation and development by ovarian signaling pathways
RD Prasasya, KE Mayo - The ovary, 2019 - Elsevier
The follicle is the functional unit of the mammalian ovary and serves as a tightly controlled
microenvironment where granulosa cells nurture the growth and maturation of the oocyte …
microenvironment where granulosa cells nurture the growth and maturation of the oocyte …
[HTML][HTML] Novel alanyl-tRNA synthetase 2 (AARS2) homozygous mutation in a consanguineous Chinese family with premature ovarian insufficiency
Y Zhou, B Chen, L Li, H Pan, B Liu, T Li, R Wang… - Fertility and …, 2019 - Elsevier
Objective To explore the candidate pathogenic gene in a premature ovarian insufficiency
(POI) proband from a consanguineous marriage and detect the potential effects of mutation …
(POI) proband from a consanguineous marriage and detect the potential effects of mutation …
Functional characterization of two new variants in the bone morphogenetic protein 7 prodomain in two pairs of monozygotic twins with hypospadias
A Bouty, K Walton, NA Listyasari… - Journal of the …, 2019 - academic.oup.com
Context Variants in bone morphogenetic protein 7 (BMP7) have been reported in patients
with hypospadias. Here we report and analyze two variants in the BMP7 prodomain in …
with hypospadias. Here we report and analyze two variants in the BMP7 prodomain in …