Optogenetic long-term depression induction in the PVT-CeL circuitry mediates decreased fear memory

M Chen, L Bi - Molecular neurobiology, 2019 - Springer
The dysregulation of fear learning and abnormal activities of cerebral networks may
contribute to the etiologies of anxiety disorders. Although it has been proposed that …

Co-exposure of metals and high fat diet causes aging like neuropathological changes in non-aged mice brain

G Iqbal, T Ahmed - Brain research bulletin, 2019 - Elsevier
In recent decades, humans' exposure to metals have increased due to industrialization and
socioeconomic trends have caused increased high fat diet (HFD) consumption …

Between an ugly truth and a perfect lie: wiping off fearful memories using beta‐adrenergic receptors antagonists

AM AlOkda, MM Nasr, SN Amin - Journal of Cellular Physiology, 2019 - Wiley Online Library
Psychiatric disorders such as anxiety, phobias, and post‐traumatic stress disorder are
considered of high global prevalence. Currently, a therapeutic approach to treat these …

[HTML][HTML] Cross-talk between guanidinoacetate neurotoxicity, memory and possible neuroprotective role of creatine

EP Marques, FS Ferreira, TM Santos, CA Prezzi… - … Et Biophysica Acta (BBA …, 2019 - Elsevier
Guanidinoacetate Methyltransferase deficiency is an inborn error of metabolism that results
in decreased creatine and increased guanidinoacetate (GAA) levels. Patients present …

Defining circuit-specific roles for G protein-coupled receptors in aversive learning

R Gowrishankar, MR Bruchas - Current opinion in behavioral sciences, 2019 - Elsevier
Highlights•Neuromodulatory circuits control the innate and learned representation of
aversive behavior.•GPCRs are essential in regulating information across key sites of …

Guanidinoacetato induz déficit de memória e neurotoxicidade em estriado de ratos: é a creatina um bom protetor?

EP Marques - 2019 - lume.ufrgs.br
A deficiência de guanidinoacetato metiltransferase (GAMT) é uma rara doença metabólica
do metabolismo da creatina que leva a níveis diminuídos de creatina e acúmulo de …

Efeitos das infusões de muscimol e AP5 no subículo dorsal sobre a aquisição ea consolidação do condicionamento de medo ao contexto em ratos

M Braga de Melo - 2019 - bdtd.ibict.br
O hipocampo dorsal (HD) é uma região fundamental no condicionamento de medo ao
contexto (CMC), provavelmente devido ao seu envolvimento com informações espaciais. A …

[引用][C] BBA-Molecular Basis of Disease

EP Marques, FS Ferreira, TM Santos, CA Prezzi…