Polymer–drug conjugate therapeutics: advances, insights and prospects
Polymer–drug conjugates have long been a mainstay of the drug delivery field, with several
conjugates successfully translated into clinical practice. The conjugation of therapeutic …
conjugates successfully translated into clinical practice. The conjugation of therapeutic …
Nanocarriers and their loading strategies
N Wang, X Cheng, N Li, H Wang… - Advanced healthcare …, 2019 - Wiley Online Library
Nanocarriers are of paramount significance for drug delivery and nanomedicine technology.
Given the imperfect systems and nonideal therapeutic effects, there are works to be done in …
Given the imperfect systems and nonideal therapeutic effects, there are works to be done in …
Application and design of esterase-responsive nanoparticles for cancer therapy
H Dong, L Pang, H Cong, Y Shen, B Yu - Drug delivery, 2019 - Taylor & Francis
Nanoparticles have been developed for tumor treatment due to the enhanced permeability
and retention effects. However, lack of specific cancer cells selectivity results in low delivery …
and retention effects. However, lack of specific cancer cells selectivity results in low delivery …
Mitochondria and plasma membrane dual-targeted chimeric peptide for single-agent synergistic photodynamic therapy
H Cheng, RR Zheng, GL Fan, JH Fan, LP Zhao… - Biomaterials, 2019 - Elsevier
Mitochondria and cell membrane play important roles in maintaining cellular activity and
stability. Here, a single-agent self-delivery chimeric peptide based nanoparticle (designated …
stability. Here, a single-agent self-delivery chimeric peptide based nanoparticle (designated …
Unadulterated BODIPY nanoparticles for biomedical applications
T Zhang, C Ma, T Sun, Z Xie - Coordination Chemistry Reviews, 2019 - Elsevier
Difluoro-4-bora-3a, 4a-diaza-s-indacene (BODIPY) as the robust dyes have been widely
applied in biomedical areas, especially for tumor imaging and phototherapy. Most of the …
applied in biomedical areas, especially for tumor imaging and phototherapy. Most of the …
Stimuli-responsive polymersomes for cancer therapy
Cancer is the most common life-threatening illness and remains the leading cause of death
in the United States. Nanomedicine represents an innovative field and has an incredible …
in the United States. Nanomedicine represents an innovative field and has an incredible …
RSM-CCD design of malachite green adsorption onto activated carbon with multimodal pore size distribution prepared from Amygdalus scoparia: Kinetic and isotherm …
In the present work, the activated carbon (AC) adsorbent with multimodal pore size
distribution prepared from Amygdalus scoparia as low-cost and locally available source was …
distribution prepared from Amygdalus scoparia as low-cost and locally available source was …
A luminescent amine-functionalized metal–organic framework conjugated with folic acid as a targeted biocompatible pH-responsive nanocarrier for apoptosis …
Folic acid amine-functionalized metal–organic framework (FOLA@ NH2-Eu: TMU-62) with
luminescent properties loaded with 5-fluorouracil (5-Fu), as an anticancer medication, was …
luminescent properties loaded with 5-fluorouracil (5-Fu), as an anticancer medication, was …
Carrier-enhanced anticancer efficacy of sunitinib-loaded green tea-based micellar nanocomplex beyond tumor-targeted delivery
N Yongvongsoontorn, JE Chung, SJ Gao, KH Bae… - Acs Nano, 2019 - ACS Publications
Although a few nanomedicines have been approved for clinical use in cancer treatment, that
recognizes improved patient safety through targeted delivery, their improved efficacy over …
recognizes improved patient safety through targeted delivery, their improved efficacy over …
[HTML][HTML] pH-and enzyme-triggered drug release as an important process in the design of anti-tumor drug delivery systems
Z Cao, W Li, R Liu, X Li, H Li, L Liu, Y Chen, C Lv… - Biomedicine & …, 2019 - Elsevier
It is necessary to design a reasonable drug delivery system (DDS) for targeted release to
overcome the potential toxicity and poor selectivity of anti-tumor drug. How a drug is …
overcome the potential toxicity and poor selectivity of anti-tumor drug. How a drug is …