Abstract Knowledge of protein–DNA binding specificity has important implications in
understanding DNA metabolism, transcriptional regulation and developing therapeutic …

A water-soluble self-assembled supramolecular FeII4L4 tetrahedron binds to single
stranded DNA, mismatched DNA base pairs, and three-way DNA junctions. Binding of the …

A single nucleotide mismatch in a particular sequence of DNA is considered to play pivotal
roles in various central biological processes and is associated with the development of …

Amido-amine macrocycles with two and four naphthalimide dyes were designed to bind
nucleoside monophosphates and oligonucleotides in an aqueous buffered solution. Anion …

The development of organic molecules to target nucleic acid is an active area of research at
the interface of chemistry and biochemistry, which involves DNA binding, nuclear imaging …

Base-pair mismatch can relieve mechanical stress in highly strained DNA molecules, but
how it affects their kinetic stability is not known. Using single-molecule fluorescence …

DNA mismatches are highly polymorphic and dynamic in nature, albeit poorly characterized
structurally. We utilized the antitumour antibiotic CoII (Chro) 2 (Chro= chromomycin A3) to …

The early detection of DNA mutations such as DNA mismatches is of major interest. Indeed,
the accumulation of mismatches into the genome arises from deficiencies of the cellular …

Here, we found that Thioflavin T (ThT) could specifically bind with a G-GGG unit (named as
“Guanine Island”) in double stranded DNA (ds-DNA). Through stacking with G base via …

We describe the molecular design, synthesis, and investigation of a series of acridine-
triaminotriazine macrocycles that selectively bind to CTG trinucleotide repeats in DNA with …