Adjuvant trastuzumab regimen for HER2-positive early-stage breast cancer: a systematic review and meta-analysis

AJ Genuino, U Chaikledkaew, DO The… - Expert review of …, 2019 - Taylor & Francis
Objective: Breast cancer remains to be the globally leading female cancer. About 15% to
20% of breast cancers have human epidermal growth factor receptor 2 (HER2)-positive …

[HTML][HTML] Impact of breast cancer molecular subtypes on the incidence, kinetics and prognosis of central nervous system metastases in a large multicentre real-life …

A Darlix, G Louvel, J Fraisse, W Jacot, E Brain… - British journal of …, 2019 - nature.com
Background Metastatic breast cancer (MBC) behaviour differs depending on hormone
receptors (HR) and human epidermal growth factor receptor (HER2) statuses. Methods The …

Efficacy of neurohormonal therapies in preventing cardiotoxicity in patients with cancer undergoing chemotherapy

M Vaduganathan, SA Hirji, A Qamar, N Bajaj, A Gupta… - Cardio Oncology, 2019 - jacc.org
Objectives This study sought to assess the effects of neurohormonal therapies in preventing
cardiotoxicity in patients receiving chemotherapy. Background Various cardioprotective …

Examining the cost-effectiveness of baseline left ventricular function assessment among breast cancer patients undergoing anthracycline-based therapy

MM Abu-Khalaf, A Safonov, J Stratton, S Wang… - Breast Cancer Research …, 2019 - Springer
Background There is a lack of consensus to guide which breast cancer patients require left
ventricular function assessment (LVEF) prior to anthracycline therapy; the cost-effectiveness …

[HTML][HTML] Risk factors associated with trastuzumab-induced cardiotoxicity in patients with human epidermal growth factor receptor 2-positive breast cancer

W Abdel-Razaq, M Alzahrani, M Al Yami… - Journal of Pharmacy …, 2019 - journals.lww.com
Context: Although trastuzumab is a highly effective and selective targeted therapy for human
epidermal growth factor receptor 2 (HER2)-positive breast cancer, the drug-induced …

[HTML][HTML] The impact of targeted therapy on intracranial metastatic disease incidence and survival

AW Erickson, S Das - Frontiers in Oncology, 2019 - frontiersin.org
Intracranial metastatic disease (IMD) is a common and severe complication of primary
cancers. Current treatment options for IMD include surgical resection and radiation therapy …

[PDF][PDF] Efficacy of treatment with carvedilol in preventing early-stage left ventricular dysfunction in patients with breast cancer candidated to receive trastuzumab using …

M Moshkani Farahani, S Nourian, HR Jalalian… - Iranian Heart …, 2019 - journal.iha.org.ir
Background: Treatment-induced cardiotoxicity is one of the major side effects of
trastuzumabtreatment in patients with breast cancer. Left ventricular (LV) dysfunction is the …

[HTML][HTML] Adjuvant trastuzumab chemotherapy in early breast cancer: meta-analysis of randomised trials and cost-effectiveness analysis

TN Doan, J Barendregt - Swiss Medical Weekly, 2019 - smw.ch
BACKGROUND Trastuzumab has a large financial impact on the average cost of breast
cancer treatment. This study reassessed the cost-effectiveness of listing the drug on the …

[PDF][PDF] Adjuvant trastuzumab regimen for HER2-positive early-stage breast cancer: a systematic review and meta-analysis

A Thakkinstiana - EXPERT REVIEW OF CLINICAL …, 2019 - academia.edu
Objective: Breast cancer remains to be the globally leading female cancer. About 15% to
20% of breast cancers have human epidermal growth factor receptor 2 (HER2)-positive …

[HTML][HTML] Central nervous system failure in Korean breast cancer patients with HER2-enriched subtype: Korean radiation oncology group 16-15 multicenter …

K Kim, KH Shin, JH Kim, DH Choi, W Park… - Journal of Breast …, 2019 - ncbi.nlm.nih.gov
Purpose The purpose of this study was to evaluate the risk of central nervous system (CNS)
failure in Korean patients with human epidermal growth factor receptor 2 (HER2)-enriched …