Dysregulated autophagy as a new aspect of the molecular pathogenesis of Krabbe disease

A Del Grosso, L Angella, I Tonazzini, A Moscardini… - Neurobiology of …, 2019 - Elsevier
Krabbe disease (KD) is a childhood leukodystrophy with no cure currently available. KD is
due to a deficiency of a lysosomal enzyme called galactosyl-ceramidase (GALC) and is …

Capturing metabolism-dependent solvent dynamics in the lumen of a trafficking lysosome

F Begarani, F D'Autilia, G Signore, A Del Grosso… - ACS …, 2019 - ACS Publications
The eukaryotic cell compartmentalizes into spatially confined, membrane-enclosed,
intracellular structures (eg, organelles, endosomes, and vesicles). Here, peculiar …

Correlative Synchrotron Micro-CT and FIB-SEM Imaging for the Analysis of Multifocal Pathologies

P Parlanti, R Rigolio, G Tromba, C Manzini… - Microscopy and …, 2019 - cambridge.org
Nowadays, the correlation of different imaging techniques with the aim of overcoming the
singlemethod limits is getting increasingly widespread [1]. Correlative Light and Electron …