Posttraumatic stress disorder is associated with increased risk of ovarian cancer: a prospective and retrospective longitudinal cohort study

AL Roberts, T Huang, KC Koenen, Y Kim… - Cancer research, 2019 - AACR
Ovarian cancer is the deadliest gynecologic cancer. Chronic stress accelerates tumor
growth in animal models of ovarian cancer. We therefore postulated that posttraumatic stress …

[HTML][HTML] Germline and somatic mutations of multi-gene panel in Chinese patients with epithelial ovarian cancer: a prospective cohort study

W Li, D Shao, L Li, M Wu, S Ma, X Tan, S Zhong… - Journal of ovarian …, 2019 - Springer
Background Multiple targeted gene sequencing is seldom performed in both germline and
somatic testing for ovarian cancer. This study is to evaluate the specific genetic alterations …

The spectrum of BRCA1 and BRCA2 pathogenic sequence variants in Middle Eastern, North African, and South European countries

Y Laitman, TM Friebel, D Yannoukakos… - Human …, 2019 - Wiley Online Library
BRCA1 BRCA2 mutational spectrum in the Middle East, North Africa, and Southern Europe
is not well characterized. The unique history and cultural practices characterizing these …

Fifteen-year survival of invasive epithelial ovarian cancer in women with BRCA1/2 mutations–the National Israeli Study of Ovarian Cancer

O Lavie, A Chetrit, I Novikov, S Sadetzki… - Gynecologic …, 2019 - Elsevier
Abstract Objective Compare 5, 10 and 15 year survival in invasive epithelial ovarian cancer,
between patients with and without BRCA1/2 germ line mutation in a nonselective group of …

[HTML][HTML] Prevalence and oncologic outcomes of BRCA1/2 mutation and variant of unknown significance in epithelial ovarian carcinoma patients in Korea

JH Seo, SY Jeong, MS Kim, JH Kang… - Obstetrics & …, 2019 - synapse.koreamed.org
Objective BRCA mutational status is important in the management of ovarian cancer, but
there is a lack of evidence supporting genetic testing in Asian populations. This study was …

A general approach to detect gene (G)‐environment (E) additive interaction leveraging G‐E independence in case‐control studies

EJ Tchetgen Tchetgen, X Shi, BHW Wong… - Statistics in …, 2019 - Wiley Online Library
It is increasingly of interest in statistical genetics to test for the presence of an additive
interaction between genetic (G) and environmental (E) risk factors. In case‐control studies …

On the use of a logistic regression model in the gene-environment problem: A Bayesian approach

A Gupta, SK Upadhyay - American Journal of Mathematical and …, 2019 - Taylor & Francis
SYNOPTIC ABSTRACT The article provides the Bayes analysis of case-control data related
to growth of cancerous cells in a reproductive organ of women. It is claimed that such …

[PDF][PDF] Auswirkungen von hochintensivem körperlichem Training (HIT) auf oxidativen Stress und DNA-Reparaturkapazität bei BRCA-Mutation

SH Andreß - 2019 - oparu.uni-ulm.de
Bei einer heterozygoten loss-of-function-Mutation des Tumorsuppressorgens BRCA (Breast
Cancer Associated Gene) beträgt das Lebenszeitrisiko einer Frau für eine …

Subjective elicitation of dirichlet hyperparameters using past data: A study of ovarian cancer patients

A Gupta, SK Upadhyay - Austrian Journal of Statistics, 2019 - ajs.or.at
Elicitation of prior plays a very important role in Bayesian paradigm especially when dealing
with rare disease problems in medical field. The reason being that we do not get enough …

Ovary and fallopian tubes

DD ROSA, AR CLAMP, GC JAYSON - api.taylorfrancis.com
The incidence of ovarian cancer varies across the world. It is highest in the USA, Europe and
Israel, and lowest in Japan and in developing countries. Ovarian cancer is the fifth most …