Pertussis is an acute respiratory disease caused by Bordetella pertussis. Due to its
frequency and severity, prevention of pertussis has been considered an important public …

Although vaccination has been effective, Bordetella pertussis is increasingly causing
epidemics, especially in industrialized countries using acellular vaccines (aPs). One factor …

Macrolides such as erythromycin are the empirical treatment of Bordetella pertussis
infections. China has experienced an increase in erythromycin-resistant B. pertussis isolates …

Background: The global resurgence of pertussis in countries with high vaccination coverage
has been a concern of public health. Methods: Nasopharyngeal swabs were collected for …

Pertussis resurgence had been attributed to waning vaccine immunity and Bordetella
pertussis adaptation to escape vaccine-induced immunity. Circulating bacteria differ …

Pertussis is a highly contagious respiratory infection caused by the bacterium Bordetella
pertussis. Humans are the only known natural reservoir of B. pertussis. In mice …

Pertussis (“whooping cough”) is a re-emerging disease with increasing incidence among
fully vaccinated individuals. We explored the genetic diversity of five Bordetella pertussis …

Background: Pertussis is a highly contagious infectious disease which continues to be an
important public-health issue despite the high immunization coverage rates achieved …

Many vaccines have heterogeneous effects across individuals. Additionally, some vaccines
do not prevent infection, but reduce disease-associated mortality and transmission. Both of …

The evolution of Bordetella pertussis from a common ancestor similar to Bordetella
bronchiseptica has occurred through large-scale gene loss, inactivation and …