Biological products: cellular therapy and FDA approved products
A Golchin, TZ Farahany - Stem cell reviews and reports, 2019 - Springer
The pace of advances in the world of science have created new opportunities and insights
that give us new and more understanding of our nature and environment. Among the …
that give us new and more understanding of our nature and environment. Among the …
The clinical trials of mesenchymal stem cell therapy in skin diseases: an update and concise review
The skin is one of the crucial body organs with anatomy and physiology linked to various
disorders including congenital and acquired diseases. Nowadays, mesenchymal stem cell …
disorders including congenital and acquired diseases. Nowadays, mesenchymal stem cell …
[HTML][HTML] Human amniotic epithelial cell-derived exosomes restore ovarian function by transferring microRNAs against apoptosis
Q Zhang, J Sun, Y Huang, S Bu, Y Guo, T Gu… - … Therapy-Nucleic Acids, 2019 - cell.com
Premature ovarian failure (POF) is one of the most common complications among female
patients with tumors treated with chemotherapy and requires advanced treatment strategies …
patients with tumors treated with chemotherapy and requires advanced treatment strategies …
Secretome of mesenchymal stem cells and its potential protective effects on brain pathologies
E Baez-Jurado, O Hidalgo-Lanussa… - Molecular …, 2019 - Springer
Previous studies have indicated that mesenchymal stem cells (MSCs) have a fundamental
role in the repair and regeneration of damaged tissues. There is strong evidence showing …
role in the repair and regeneration of damaged tissues. There is strong evidence showing …
[HTML][HTML] Profiling of RNAs from human islet-derived exosomes in a model of type 1 diabetes
P Krishnan, F Syed, N Jiyun Kang, R G. Mirmira… - International journal of …, 2019 - mdpi.com
Type 1 diabetes (T1D) is characterized by the immune-mediated destruction of insulin-
producing islet β cells. Biomarkers capable of identifying T1D risk and dissecting disease …
producing islet β cells. Biomarkers capable of identifying T1D risk and dissecting disease …
[HTML][HTML] Extracellular vesicles expressing a single-chain variable fragment of an HIV-1 specific antibody selectively target Env+ tissues
X Zou, M Yuan, T Zhang, H Wei, S Xu, N Jiang… - Theranostics, 2019 - ncbi.nlm.nih.gov
Rationale: Antiretroviral therapy can effectively suppress HIV-1 replication in the peripheral
blood to an undetectable level. However, elimination of the latent virus in reservoirs remains …
blood to an undetectable level. However, elimination of the latent virus in reservoirs remains …
The effects of cell type and culture condition on the procoagulant activity of human mesenchymal stromal cell-derived extracellular vesicles
TC Chance, CR Rathbone… - Journal of Trauma …, 2019 - journals.lww.com
BACKGROUND Mesenchymal stromal cell (MSC)-derived extracellular vesicles (EVs) have
great potential as a cell-free therapy in wound healing applications. Because EV …
great potential as a cell-free therapy in wound healing applications. Because EV …
The relationship between molecular content of mesenchymal stem cells derived exosomes and their potentials: opening the way for exosomes based therapeutics
At least, more than half of our understanding of extracellular vesicles owes to the studies
conducted over the past few years. When it became clear that the exosomes have various …
conducted over the past few years. When it became clear that the exosomes have various …
Extracellular vesicles, news about their role in immune cells: physiology, pathology and diseases
J Meldolesi - Clinical & Experimental Immunology, 2019 - academic.oup.com
Two types of extracellular vesicles (EVs), exosomes and ectosomes, are generated and
released by all cells, including immune cells. The two EVs appear different in many …
released by all cells, including immune cells. The two EVs appear different in many …
[HTML][HTML] Annexin A1 contained in extracellular vesicles promotes the activation of keratinocytes by mesoglycan effects: an autocrine loop through FPRs
E Pessolano, R Belvedere, V Bizzarro, P Franco… - Cells, 2019 - mdpi.com
We have recently demonstrated that mesoglycan, a fibrinolytic compound, may be a
promising pro-healing drug for skin wound repair. We showed that mesoglycan induces …
promising pro-healing drug for skin wound repair. We showed that mesoglycan induces …