[HTML][HTML] Casting a wider net: Immunosurveillance by nonclassical MHC molecules
Most studies of T lymphocytes focus on recognition of classical major histocompatibility
complex (MHC) class I or II molecules presenting oligopeptides, yet there are numerous …
complex (MHC) class I or II molecules presenting oligopeptides, yet there are numerous …
[HTML][HTML] The emerging roles of human leukocyte antigen-F in immune modulation and viral infection
A Lin, WH Yan - Frontiers in immunology, 2019 - frontiersin.org
Human leukocyte antigens (HLAs) play various critical roles in both innate and adaptive
immunity through processes such as presenting antigens to T cells and serving as ligands …
immunity through processes such as presenting antigens to T cells and serving as ligands …
HLA-F on autologous HIV-infected cells activates primary NK cells expressing the activating killer immunoglobulin-like receptor KIR3DS1
Z Kiani, J Bruneau, DE Geraghty, NF Bernard - Journal of virology, 2019 - Am Soc Microbiol
ABSTRACT HIV-exposed seronegative KIR3DS1 homozygotes have a reduced risk of HIV
infection. HLA-F is the ligand for the activating NK cell receptor (NKR) KIR3DS1. HLA-F is …
infection. HLA-F is the ligand for the activating NK cell receptor (NKR) KIR3DS1. HLA-F is …
[HTML][HTML] European patent in immunoncology: from immunological principles of implantation to cancer treatment
FM Würfel, C Winterhalter, P Trenkwalder… - International journal of …, 2019 - mdpi.com
The granted European patent EP 2 561 890 describes a procedure for an immunological
treatment of cancer. It is based on the principles of the HLA-supported communication of …
treatment of cancer. It is based on the principles of the HLA-supported communication of …
HLA-F displays highly divergent and frequent haplotype lineages associated with different mRNA expression levels
HLA-F is one of the most conserved loci among the HLA gene family. The exact function of
HLA-F is still under investigation. HLA-F might present tolerogenic features, participate in the …
HLA-F is still under investigation. HLA-F might present tolerogenic features, participate in the …
[HTML][HTML] HLA-F allele-specific peptide restriction represents an exceptional proteomic footprint
GGT Hò, FJ Heinen, R Blasczyk, A Pich… - International Journal of …, 2019 - mdpi.com
Peptide-dependent engagement between human leucocyte antigens class I (HLA-I)
molecules and their cognate receptors has been extensively analyzed. HLA-F belongs to the …
molecules and their cognate receptors has been extensively analyzed. HLA-F belongs to the …
Blocking 'don't eat me'signals CD47 and LILRB2 to enhance macrophage-and granulocyte-mediated phagocytosis of cancer cells
BMT Nguyen - 2019 - ucg.studenttheses.ub.rug.nl
Cancer cells can evade immune surveillance by utilizing surface receptors called immune
checkpoints. CD47 and LILRB2 are two of the few receptors that can provide an inhibitory …
checkpoints. CD47 and LILRB2 are two of the few receptors that can provide an inhibitory …
Immune-driven positive and balancing selection in human populations
S Kaewert - 2019 - repository.cam.ac.uk
This thesis examines the evidence for positive and balancing selection on immune genes in
388 individuals grouped into thirteen geographically diverse populations. The data are high …
388 individuals grouped into thirteen geographically diverse populations. The data are high …
Casting a wider net: Immunosurveillance by nonclassical MHC molecules
ME Birnbaum - 2019 - dspace.mit.edu
Most studies of T lymphocytes focus on recognition of classical major histocompatibility
complex (MHC) class I or II molecules presenting oligopeptides, yet there are numerous …
complex (MHC) class I or II molecules presenting oligopeptides, yet there are numerous …
[图书][B] NK cell subset responses to HIV
Z Kiani - 2019 - search.proquest.com
In 2017 around 37 million people worldwide were living with HIV and 1.8 million new
infections occurred. Therefore, HIV infection continues to be an important global human …
infections occurred. Therefore, HIV infection continues to be an important global human …