Cardiovascular calcification is a health disorder with increasing prevalence and high
morbidity and mortality. The only available therapeutic options for calcific vascular and …

This article focuses on the relevance of amorphous calcium (and magnesium) phosphates in
living organisms. Although crystalline calcium phosphate (CaP)-based materials are known …

Chronic kidney disease (CKD) is one of the most powerful predictors of premature
cardiovascular disease (CVD), with heightened susceptibility to vascular intimal and medial …

The physicochemical deposition of calcium-phosphate in the arterial wall is prevented by
calcification inhibitors. Studies in cohorts of patients with rare genetic diseases have shed …

Alpha 2-Heremans-Schmid glycoprotein, also known as fetuin-A (Fet-A), is a multifunctional
plasma glycoprotein that has been identified in both animal and human beings. The protein …

Patients with chronic kidney disease (CKD) are at increased risk of osteoporosis and
vascular calcification. Bone demineralization and vascular mineralization go often hand in …

Fetuin-A, also termed alpha2-Heremans-Schmid glycoprotein, is a 46 kDa hepatocyte
derived protein (hepatokine) and serves multifaceted functions.(i) It acts as systemic inhibitor …

Risk prediction of future atherothrombotic cardiovascular events is currently based on
conventional risk factor assessment and the use of validated algorithms, such as the …

The increase in prevalence and severity of vascular calcification in chronic kidney disease is
a result of complex interactions between changes in the vascular bed, mineral metabolites …

Magnesium is essential for many physiological functions in the human body. Its homeostasis
involves dietary intake, absorption, uptake and release from bone, swifts between the intra …