Excessive adiposity raises blood pressure and accounts for 65–75% of primary
hypertension, which is a major driver of cardiovascular and kidney diseases. In obesity …

Resistant hypertension (RHTN) is defined as uncontrolled blood pressure despite the use
of≥ 3 antihypertensive agents of different classes, including a diuretic, usually thiazide-like …

Background Spironolactone is effective at reducing blood pressure in patients with
uncontrolled resistant hypertension. However, the use of spironolactone in patients with …

In 2018, the American Heart Association published a Scientific Statement on resistant
hypertension. We compared the prevalence of apparent treatment-resistant hypertension …

Diuretics are listed in hypertension guidelines as one of three equally weighted first-line
treatment options. In order to differentiate between antihypertensives, a lot of discussion has …

Hyperkalemia (HK) is the most common electrolyte disturbance observed in patients with
kidney disease, particularly in those in whom diabetes and heart failure are present or are …

Hypertension is the most common chronic disease and the leading risk factor for disability
and premature deaths in the world, accounting for more than 9 million deaths annually …

2019 Chinese guideline for the management of hypertension in the elderly - PMC Back to
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Context Classical apparent mineralocorticoid excess (AME) is a rare recessive disorder,
caused by severe 11β-hydroxysteroid dehydrogenase type 2 enzyme (11 β-HSD2) …

Abstract Purpose of Review To review comparative efficacy and tolerability data between the
two main mineralocorticoid receptor antagonists (MRAs), spironolactone and eplerenone, in …