Bridging inhaled aerosol dosimetry to physiologically based pharmacokinetic modeling for toxicological assessment: nicotine delivery systems and beyond

AR Kolli, AK Kuczaj, F Martin, AW Hayes… - Critical Reviews in …, 2019 - Taylor & Francis
One of the challenges for toxicological assessment of inhaled aerosols is to accurately
predict their deposited and absorbed dose. Transport, evolution, and deposition of liquid …

[HTML][HTML] Model-based drug development in pulmonary delivery: pharmacokinetic analysis of novel drug candidates for treatment of Pseudomonas aeruginosa lung …

T Sou, I Kukavica-Ibrulj, F Soukarieh, N Halliday… - Journal of …, 2019 - Elsevier
Antibiotic resistance is a major public health threat worldwide. In particular, about 80% of
cystic fibrosis patients have chronic Pseudomonas aeruginosa (PA) lung infection resistant …