Phenazine Antibiotic‐Inspired Discovery of Bacterial Biofilm‐Eradicating Agents

RW Huigens III, Y Abouelhassan, H Yang - ChemBioChem, 2019 - Wiley Online Library
Bacterial biofilms are surface‐attached communities of slow‐growing and non‐replicating
persister cells that demonstrate high levels of antibiotic tolerance. Biofilms occur in nearly …

Cadexomer iodine effectively reduces bacterial biofilm in porcine wounds ex vivo and in vivo

ED Roche, EJ Woodmansey, Q Yang… - International wound …, 2019 - Wiley Online Library
Biofilms are prevalent in non‐healing chronic wounds and implicated in delayed healing.
Tolerance to antimicrobial treatments and the host's immune system leave clinicians with …

[HTML][HTML] The Long-Term Persistence of Borrelia burgdorferi Antigens and DNA in the Tissues of a Patient with Lyme Disease

E Sapi, RS Kasliwala, H Ismail, JP Torres… - Antibiotics, 2019 - mdpi.com
Whether Borrelia burgdorferi, the causative agent of Lyme disease, can persist for long
periods in the human body has been a controversial question. The objective of this study …

The impact of biofilm formation on wound healing

RA Mendoza, J Hsieh, RD Galiano - Wound healing-current …, 2019 - books.google.com
Chronic wounds represent an important challenge for wound care and are universally
colonized by bacteria. These bacteria can form biofilm as a survival mechanism that confers …

[HTML][HTML] Drug leaching properties of Vancomycin loaded mesoporous hydroxyapatite as bone substitutes

JA Lett, S Sagadevan, JJ Prabhakar, NA Hamizi… - Processes, 2019 - mdpi.com
Infections after bone reconstructive surgery become an authentic therapeutic and economic
issue when it comes to a modern health care system. In general; infected bone defects are …

[HTML][HTML] Chronic wound microbiome colonization on mouse model following cryogenic preservation

CD Tipton, NE Sanford, JA Everett, RA Gabrilska… - PLoS …, 2019 - journals.plos.org
Chronic wound infections are increasingly recognized to be dynamic and polymicrobial in
nature, necessitating the development of wound models which reflect the complexities of …

Medical biofilms

KD Mandakhalikar - Introduction to Biofilm Engineering, 2019 - ACS Publications
Biofilm formation by bacteria plays a very important role in healthcare-associated infections.
It enhances their pathogenesis and severity and causes remarkable human morbidity and …

An equine wound model to study effects of bacterial aggregates on wound healing

E Jørgensen, L Bay, LT Skovgaard… - Advances in Wound …, 2019 - liebertpub.com
Objective: Relevant animal models to study effects of bacterial aggregates on wound
healing are lacking. We aimed at establishing an equine wound model with bacterial …

[PDF][PDF] Reduction of biofilm in chronic wounds by antibacterial protease combined with silver dressing

M Wei, Q Jiang, N Niu, L Dong, L Wang, W Chen… - Int J Clin Exp …, 2019 - e-century.us
To evaluate the efficacy of antibacterial protease combined with silver dressing on biofilm
reduction and healing in chronic wounds. A pilot, single-blinded randomized controlled trial …

Application of alginate oligosaccharides and sodium alginate in breast abscess incision and drainage

Y Miao, T Sun, G Sun - IOP Conference Series: Materials Science …, 2019 - iopscience.iop.org
Objective: To evaluate the efficacy of alginate oligosaccharides and sodium alginate
(seaweed biological glue) after incision drainage for breast abscess. Methods: randomly …