Optimizing oncolytic virotherapy in cancer treatment
K Harrington, DJ Freeman, B Kelly, J Harper… - Nature reviews Drug …, 2019 - nature.com
In the wake of the success of modern immunotherapy, oncolytic viruses (OVs) are currently
seen as a potential therapeutic option for patients with cancer who do not respond or fail to …
seen as a potential therapeutic option for patients with cancer who do not respond or fail to …
Phase I trial of an ICAM-1-targeted immunotherapeutic-coxsackievirus A21 (CVA21) as an oncolytic agent against non muscle-invasive bladder cancer
NE Annels, D Mansfield, M Arif… - Clinical Cancer …, 2019 - AACR
Abstract Purpose: The CANON [CA VATAK in NON–muscle-invasive bladder cancer
(NMIBC)] study evaluated a novel ICAM-1–targeted immunotherapeutic-coxsackievirus A21 …
(NMIBC)] study evaluated a novel ICAM-1–targeted immunotherapeutic-coxsackievirus A21 …
Oncolytic Maraba virus armed with tumor antigen boosts vaccine priming and reveals diverse therapeutic response patterns when combined with checkpoint blockade …
AJR McGray, RY Huang, S Battaglia, C Eppolito… - … for immunotherapy of …, 2019 - Springer
Background Cancer immunotherapies are emerging as promising treatment strategies for
ovarian cancer patients that experience disease relapse following first line therapy. As such …
ovarian cancer patients that experience disease relapse following first line therapy. As such …
Oncolytic immunotherapy and bortezomib synergy improves survival of refractory multiple myeloma in a preclinical model
CM Thirukkumaran, ZQ Shi, GJ Nuovo… - Blood …, 2019 - ashpublications.org
The oncolytic reovirus (RV) has demonstrated clinical efficacy and minimal toxicity in a
variety of cancers, including multiple myeloma (MM). MM is a malignancy of plasma cells …
variety of cancers, including multiple myeloma (MM). MM is a malignancy of plasma cells …
Virotherapy-recruited PMN-MDSC infiltration of mesothelioma blocks antitumor CTL by IL-10-mediated dendritic cell suppression
Z Tan, L Liu, MS Chiu, KW Cheung, CW Yan… - …, 2019 - Taylor & Francis
Antitumor cytotoxic T lymphocytes (CTLs) are essential for immune surveillance, yet the
blockade of eliciting such CTLs during oncolytic virotherapy remains incompletely …
blockade of eliciting such CTLs during oncolytic virotherapy remains incompletely …
Oncolytic Virus Immunotherapy in Sarcoma
V Monga, SM Maliske, M Milhem - Immunotherapy of Sarcoma, 2019 - Springer
Oncolytic viruses (OVs) are tumor-specific, live agents that actively replicate and function to
kill cancer and associated stromal cells through a dual mechanism—a direct, cytotoxic effect …
kill cancer and associated stromal cells through a dual mechanism—a direct, cytotoxic effect …
[PDF][PDF] Evolution and effectiveness of oncolytic virotherapy as a cancer treatment
D Perera, S Dias - Int J Radiol Radiat Ther, 2019 - researchgate.net
Cancer is a condition characterized as the uncontrolled cell proliferation, which can be
induced by a vast number of factors such as chemicals, radiation, hereditary factors etc. Over …
induced by a vast number of factors such as chemicals, radiation, hereditary factors etc. Over …
[图书][B] Untersuchungen kaniner histiozytärer Neoplasien unter besonderer Berücksichtigung des Tumormikromilieus und des Einsatzes viraler Onkolyse
C Puff - 2019 - elib.tiho-hannover.de
Maligne Neoplasien stellen nach wie vor eine der häufigsten Todesursachen bei Hunden
und Menschen dar. Trotz umfangreicher Studien in den letzten Jahren führt bei vielen …
und Menschen dar. Trotz umfangreicher Studien in den letzten Jahren führt bei vielen …