Extreme atherosclerotic cardiovascular disease (ASCVD) risk recognition
PD Rosenblit - Current diabetes reports, 2019 - Springer
Abstract Purpose of Review To distinguish extreme and very high atherosclerotic
cardiovascular disease (ASCVD) event risk based on prospective epidemiological studies …
cardiovascular disease (ASCVD) event risk based on prospective epidemiological studies …
Optimizing dyslipidemia management for the prevention of cardiovascular disease: a focus on risk assessment and therapeutic options
AN Berman, R Blankstein - Current cardiology reports, 2019 - Springer
Primary prevention of incident atherosclerotic cardiovascular disease (ASCVD) as well as
decreasing the risk of future events in those with established atherosclerosis is critical from a …
decreasing the risk of future events in those with established atherosclerosis is critical from a …
Familial hypercholesterolemia among young adults with myocardial infarction
Background: There are limited data on the prevalence and treatment of familial
hypercholesterolemia (FH) among US adults who experience a myocardial infarction (MI) at …
hypercholesterolemia (FH) among US adults who experience a myocardial infarction (MI) at …
Prevalence and cardiovascular health impact of family history of premature heart disease in the United States: analysis of the national health and nutrition examination …
R Moonesinghe, Q Yang, Z Zhang… - Journal of the American …, 2019 - Am Heart Assoc
Background Because family history is a known risk factor for heart disease, it is important to
characterize its public health impact in terms of population prevalence of family history of …
characterize its public health impact in terms of population prevalence of family history of …
Computationally driven structure optimization, synthesis, and biological evaluation of imidazole-based proprotein convertase subtilisin/kexin 9 (PCSK9) inhibitors
C Lammi, J Sgrignani, A Arnoldi, G Lesma… - Journal of medicinal …, 2019 - ACS Publications
Proprotein convertase subtilisin/kexin 9 (PCSK9) is responsible for the degradation of the
hepatic low-density lipoprotein receptor (LDLR), which in turn regulates the circulating low …
hepatic low-density lipoprotein receptor (LDLR), which in turn regulates the circulating low …
A review of gene-and cell-based therapies for familial hypercholesterolemia
Familial hypercholesterolemia (FH) is a genetic autosomal dominant disorder caused by an
impaired receptor-mediated low-density lipoprotein (LDL) removal from the circulation …
impaired receptor-mediated low-density lipoprotein (LDL) removal from the circulation …
Hidden Burden of Electronic Health Record‐Identified Familial Hypercholesterolemia: Clinical Outcomes and Cost of Medical Care
Background Familial hypercholesterolemia (FH), is a historically underdiagnosed,
undertreated, high‐risk condition that is associated with a high burden of cardiovascular …
undertreated, high‐risk condition that is associated with a high burden of cardiovascular …
The prevalence and related factors of familial hypercholesterolemia in rural population of China using Chinese modified Dutch Lipid Clinic Network definition
Y Wang, Y Li, X Liu, R Tu, H Zhang, X Qian, J Jiang… - BMC Public Health, 2019 - Springer
Background Familial hypercholesterolemia (FH) is a common monogenic disease, while
studies about the epidemiology for the general population in China was scarce. Aim of the …
studies about the epidemiology for the general population in China was scarce. Aim of the …
Risk communication in families of children with familial hypercholesterolemia: identifying motivators and barriers to cascade screening to improve diagnosis at a single …
E Wurtmann, J Steinberger, PMC Veach… - Journal of Genetic …, 2019 - Wiley Online Library
Familial hypercholesterolemia (FH) is severely underdiagnosed in the USA; yet, factors
influencing family notification about risk for FH in the US pediatric setting have not been well …
influencing family notification about risk for FH in the US pediatric setting have not been well …
The curative treatment of familial hypercholesterolemia: Liver transplantation
N Gulsoy Kirnap, M Kirnap… - Clinical …, 2019 - Wiley Online Library
Background Familial hypercholesterolemia (FH) is an autosomal dominant genetic disorder
characterized by premature mortal cardiovascular complications. Liver transplantation (LT) …
characterized by premature mortal cardiovascular complications. Liver transplantation (LT) …