Dietary natural flavonoids treating cancer by targeting aryl hydrocarbon receptor

T Yang, YL Feng, L Chen, ND Vaziri… - Critical reviews in …, 2019 - Taylor & Francis
The role of aryl hydrocarbon receptor (AhR) as a ligand-activated transcription factor in the
field of cancer has gradually been unveiled. A strong body of evidence indicated that AhR is …

[HTML][HTML] Simulated microgravity promotes the formation of tridimensional cultures and stimulates pluripotency and a glycolytic metabolism in human hepatic and biliary …

D Costantini, D Overi, L Casadei, V Cardinale, L Nevi… - Scientific reports, 2019 - nature.com
Many pivotal biological cell processes are affected by gravity. The aim of our study was to
evaluate biological and functional effects, differentiation potential and exo-metabolome …

Aryl-hydrocarbon receptor as a potential target for anticancer therapy

JE Vorontsova, RO Cherezov, BA Kuzin… - … ), Supplement Series B …, 2019 - Springer
Aryl-hydrocarbon receptor (A ryl H ydrocarbon R eceptor, AHR) is a ligand-dependent
transcription factor; its functions are related to xenobiotic detoxification, response to …

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) Disrupts Control of Cell Proliferation and Apoptosis in a Human Model of Adult Liver Progenitors

J Svobodová, J Procházková, M Kabátková… - Toxicological …, 2019 - academic.oup.com
The aryl hydrocarbon receptor (AhR) activation has been shown to alter proliferation,
apoptosis, or differentiation of adult rat liver progenitors. Here, we investigated the impact of …

Transition from normal to cancerous cell by precancerous niche (PCN) induced chronic cell-matrix stress

BLDM Brücher, IS Jamall - 4open, 2019 - 4open-sciences.org
The attempt to restore homeostasis, once disrupted, such that complex signaling, crosstalk
between ubiquitous proteins, and a diverse range of pathways gone awry is near …

2, 3, 7, 8‐Tetrachlorodibenzo‐p‐dioxin promotes injury‐induced vascular neointima formation in mice

S Guo, R Zhang, Q Liu, Q Wan, Y Wang… - The FASEB …, 2019 - Wiley Online Library
ABSTRACT 2, 3, 7, 8‐Tetrachlorodibenzo‐p‐dioxin (TCDD) is an environmental pollutant
that causes cardiovascular toxicity. The phenotypic transformation of vascular smooth …

Genome-scale Approaches to Identifying Novel Regulators of Fibrolamellar Carcinoma

T Dinh - 2019 - cdr.lib.unc.edu
Fibrolamellar carcinoma (FLC) is a rare liver cancer that primarily affects adolescents and
young adults without any prior history of liver disease. First-line treatment of FLC is surgical …

Stem/progenitor cells from duodenal brunner's glands and methods of isolating and using them

G Carpino, V Cardinale, LM Reid, D Alvaro, E Gaudio - 2019 - Google Patents
stem/progenitor cell niches persist in specific anatomical locations within the fetal and
postnatal human biliary tree. Although stem/progenitor cell populations have long been …

[引用][C] Клеточные культуры аденокарциномы толстой кишки человека как модель для изучения опухолевых стволовых клеток

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