Hypersensitivity due to central pain mechanisms can influence recovery and lead to worse
clinical outcomes, but the ability of quantitative sensory testing (QST), an index of …

Persistent, in particular neuropathic pain affects millions of people worldwide. However, the
response rate of patients to existing analgesic drugs is less than 50%. There are several …

Background Conditioned pain modulation (CPM) and offset analgesia are different features
of descending pain inhibition. This study investigated CPM, offset analgesia and clinical …

Objectives: The effects of eccentric exercises on clinical outcomes and central pain
mechanisms are unclear in neck/shoulder pain (NSP). The aims were to:(1) evaluate the …

Methods: This narrative review describes and evaluates clinical trial phases, specific POC
pain trials, and approaches to patient profiling. Results: We describe common POC trial …

Abstract Evaluation of the response to externally applied physical stimuli, such as pressure,
heat, or cold is termed quantitative sensory testing (QST). QST may be used to identify and …

Background: Abdominal pain is the most common symptom in chronic pancreatitis (CP) and
has an extensive impact on patients' lives. Quantitative sensory testing (QST) provides …

Abstract EDITOR'S PERSPECTIVE What We Already Know about This Topic The
prevalence of patients prescribed buprenorphine for treatment of opioid use disorder is …

BACKGROUND The clinical relevance of the suggested hyperalgesic effects of remifentanil
is still unclear, especially in the long term. OBJECTIVE The current study evaluated the …

Quantitative sensory testing (QST) is used in a variety of pain disorders to characterize pain
and predict prognosis and response to specific therapies. In this study, we aimed to confirm …