To maintain physiological homeostasis, cell turnover occurs every day in the body via a form
of programmed cell death called apoptosis. During apoptosis, cells undergo distinct …

Microparticles are a distinctive group of small vesicles, without nucleus, which are involved
as significant modulators in several physiological and pathophysiological mechanisms …

Hypoxia, as one of the severe cellular stresses, can cause cellular injury and even cell
death. Apoptosis is the main mechanism of regulating cell death and is closely related to the …

Extracellular vesicles (EVs) are mRNA-containing cell fragments shed into circulation during
pathophysiological events. DNA methyltransferases (DNMT1, DNMT3A, and DNMT3B) …

We recently demonstrated that circulating microparticles (MPs) from patients with valvular
heart diseases (VHD) subjected to cardiac surgery impaired endothelial function and …

Microparticles (MPs) are small vesicles shed from the cytoplasmic membrane of healthy,
activated, or apoptotic cells. MPs are very heterogeneous in size (100–1,000 nm), and they …

The activation of protease-activated receptor (PAR)-2 by factor Xa (fXa) promotes the
release of tissue factor-positive microvesicles (TF+ MV), and contributes to proliferation in …

Endothelial dysfunction is one of the primary factors in the onset and progression of
atherothrombosis resulting in acute myocardial infarction (AMI). However, the pathological …

Tissue factor (TF)-positive microvesicles from various sources can promote cellular
proliferation or alternatively induce apoptosis, but the determining factors are unknown. In …

Endothelial dysfunction is a hallmark of diabetic vascular complications. Microparticles
(MPs) are small vesicles shed from the surface of blood and vascular cells that act as stimuli …