[HTML][HTML] Psychotropics and the microbiome: a chamber of secrets…

S Cussotto, G Clarke, TG Dinan, JF Cryan - Psychopharmacology, 2019 - Springer
The human gut contains trillions of symbiotic bacteria that play a key role in programming
different aspects of host physiology in health and disease. Psychotropic medications act on …

Recent advancements in mechanistic studies and structure activity relationship of FoF1 ATP synthase inhibitor as antimicrobial agent

R Narang, R Kumar, S Kalra, SK Nayak… - European Journal of …, 2019 - Elsevier
The emergence of drug resistance in infectious microbial strains can be overcome by
development of novel drug molecules against unexploited microbial target. The success of …

[HTML][HTML] Dos distúrbios psiquiátricos à antibioticoterapia: reposicionamento da clorpromazina como agente antibacteriano

WG Lima, MC Ramos-Alves, AC Soares - Revista Colombiana de …, 2019 - scielo.org.co
RESUMO O alarmante aumento na taxa de resistência aos antibióticos põe em check à
eficácia da terapia antibacteriana futura. Em contrapartida, as indústrias farmacêuticas …

Efflux Pump Inhibitors, Alpha-Tocopherol and Aspirin: Role in Campylobacter jejuni and Campylobacter coli Fluoroquinolone Resistance

AA Abd El-Tawab, AM Ammar, HA Ahmed… - Microbial Drug …, 2019 - liebertpub.com
This study aimed to investigate how efflux pump activity contributes to high fluoroquinolone
(FQ) resistance in Campylobacter jejuni and Campylobacter coli isolates and to evaluate the …

Effect of various drugs on differentially detectable persisters of Mycobacterium tuberculosis generated by long-term lipid diet

SR Khan, U Venugopal, G Chandra, S Bharti… - Tuberculosis, 2019 - Elsevier
Abstract Persisters of Mycobacterium tuberculosis (Mtb) that fail to form colonies on agar
media when de-stressed are termed as differentially d etectable (DD) persisters. Since in the …

From psychiatric disorders to antibiotic therapy: repositioning of chlorpromazine as an antibacterial agent

WG Lima, MC Ramos-Alves, AC Soares - Revista Colombiana de …, 2019 - scielo.org.co
Abstract LIMA, William Gustavo; RAMOS-ALVES, Maria Cristina and SOARES, Adriana
Cristina. From psychiatric disorders to antibiotic therapy: repositioning of chlorpromazine as …

In vitro and in vivo toxicity evaluation of non-neuroleptic phenothiazines, antitubercular drug candidates

S Salie, A Labuschagné, A Walters, S Geyer… - Regulatory Toxicology …, 2019 - Elsevier
The phenothiazine-derived antipsychotic drugs, such as chlorpromazine and thioridazine,
are bactericidal against drug-sensitive and drug-resistant strains of Mycobacterium …

Clinical management of drug-resistant Mycobacterium tuberculosis strains: pathogen-targeted versus host-directed treatment approaches

H Al-Ghafli, S Al-Hajoj - Current Pharmaceutical Biotechnology, 2019 - ingentaconnect.com
Background: Despite exerted efforts to control and treat Mycobacterium tuberculosis (MTB)
strains, Tuberculosis (TB) remains a public health menace. The emergence of complex drug …

Antibacterial properties of thioridazine

N Hrynchuk, N Vrynchanu - Farmatsevtychnyi zhurnal, 2019 - pharmj.org.ua
УДК 615.214.21:579.8 DOI: 10.32352/0367-3057.4.19.11 НІГРИНЧУК (https://orcid.org/0000-0002-2069-5917),
Н. Page 1 96 ISSN 0367-3057, Фармацевтичний журнал, 2019, № 4 © НІГринчук, НОВринчану …

Recent Advances in Repositioning Non-Antibiotics against Tuberculosis and other Neglected Tropical Diseases

MMD Semenya - Medicinal Chemistry of Neglected and Tropical …, 2019 - taylorfrancis.com
Multiple tuberculosis (TB) drug development campaigns capitalize on drugs already
approved by regulatory authorities including those originally indicated for diseases of a non …