Summary Each year, the American Heart Association (AHA), in conjunction with the National
Institutes of Health and other government agencies, brings together in a single document the …

Type 2 diabetes mellitus is a risk factor for incident heart failure and increases the risk of
morbidity and mortality in patients with established disease. Secular trends in the …

Adolescence is a time of change: changes to hormones and the body, changes in the social
environment, and changes to the brain and the mind. Although most young people develop …

Multiple sclerosis (MS) is a neuroinflammatory disease with a relapsing–remitting disease
course at early stages, distinct lesion characteristics in cortical grey versus subcortical white …

Purpose Chronic wounds are a major public health challenge, but little is known about the
true burden with studies reporting different estimates because of disparities in study designs …

With growing interest in the gut microbiome, prebiotics and probiotics have received
considerable attention as potential treatments for depression and anxiety. We conducted a …

Background No previous systematic review has quantitatively examined the association
between muscular fitness during childhood and adolescence and health parameters later in …

Key Clinical Points Depression in the Primary Care Setting Screening for depression and
suicidal thinking and behavior is important in the primary care setting. Distinguishing …

The relationships between sedentary lifestyle, sitting behaviour, and low back pain (LBP)
remain controversial. In this study, we investigated the relationship between back pain and …

Type 2 diabetes mellitus (T2DM) is an ensemble of metabolic diseases that has reached
pandemic dimensions all over the world. The multifactorial nature of the pathology makes …