AIM2 is a cytosolic innate immune receptor which recognizes double‐stranded DNA
(dsDNA) released during cellular perturbation and pathogenic assault. AIM2 recognition of …

The recognition that atherosclerosis is a complex chronic inflammatory disorder mediated
through both adaptive and innate immunity has led to the hypothesis that anticytokine …

Inflammation is a well‐known feature of heart failure. Studies have shown that while some
inflammation is required for repair during injury and is protective, prolonged inflammation …

Air pollution is the most important environmental risk factor for disease and premature death,
and exposure to combustion particles from vehicles is a major contributor. Human …

Abstract Background Apabetalone (RVX-208) is a bromodomain and extraterminal protein
inhibitor (BETi) that in phase II trials reduced the relative risk (RR) of major adverse cardiac …

Chemokines orchestrate leukocyte recruitment in atherosclerosis and their blockade is a
promising anti-atherosclerotic strategy, but few chemokine-based approaches have …

Aim. Resveratrol is a natural plant polyphenol. The present study investigated the effects of
resveratrol on the Toll‐like receptor 4‐(TLR4‐) mediated expression and secretion of matrix …

The mortality rates of age-related diseases (ARDs) increase exponentially with age.
Processes described by the exponential growth function typically involve a branching chain …

The endothelial lining can be viewed as the first line of defense against risk factors of
vascular disease. Endothelial dysfunction is regarded as an initial event for atherogenesis …

Lysophosphatidic acid (LPA) is a collective name for a set of bioactive lipid species. Via six
widely distributed G protein-coupled receptors (GPCRs), LPA elicits a plethora of biological …