Cistrome partitioning reveals convergence of somatic mutations and risk variants on master transcription regulators in primary prostate tumors
Thousands of noncoding somatic single-nucleotide variants (SNVs) of unknown function are
reported in tumors. Partitioning the genome according to cistromes reveals the enrichment of …
reported in tumors. Partitioning the genome according to cistromes reveals the enrichment of …
Genome-wide mapping of nucleotide excision repair with XR-seq
Nucleotide excision repair is a versatile mechanism to repair a variety of bulky DNA adducts.
We developed excision repair sequencing (XR-seq) to study nucleotide excision repair of …
We developed excision repair sequencing (XR-seq) to study nucleotide excision repair of …
Recurrent noncoding mutations in skin cancers: UV damage susceptibility or repair inhibition as primary driver?
SA Roberts, AJ Brown, JJ Wyrick - Bioessays, 2019 - Wiley Online Library
Somatic mutations arising in human skin cancers are heterogeneously distributed across the
genome, meaning that certain genomic regions (eg, heterochromatin or transcription factor …
genome, meaning that certain genomic regions (eg, heterochromatin or transcription factor …