Pharmacological treatment of chemotherapy-induced neuropathic pain: PPARγ agonists as a promising tool

NLM Quintão, JR Santin, LC Stoeberl… - Frontiers in …, 2019 - frontiersin.org
Chemotherapy-induced neuropathic pain (CINP) is one of the most severe side effects of
anticancer agents, such as platinum-and taxanes-derived drugs (oxaliplatin, cisplatin …

Recent developments of novel pharmacologic therapeutics for prevention of chemotherapy-induced peripheral neuropathy

S Hu, KM Huang, EJ Adams, CL Loprinzi… - Clinical Cancer …, 2019 - AACR
Chemotherapy-induced peripheral neuropathy (CIPN) is a common and dose-limiting
toxicity, negatively affecting both quality of life and disease outcomes. To date, there is no …

[HTML][HTML] Alleviation of paclitaxel-induced mechanical hypersensitivity and hyperalgesic priming with AMPK activators in male and female mice

KE Inyang, TA McDougal, ED Ramirez, M Williams… - Neurobiology of Pain, 2019 - Elsevier
AMP-activated protein kinase (AMPK) is an energy-sensing kinase that has emerged as a
novel therapeutic target for pain due to its ability to inhibit mechanistic target of rapamycin …

The association between the incidence risk of peripheral neuropathy and PD-1/PD-L1 inhibitors in the treatment for solid tumor patients: a systematic review and meta …

Z Si, S Zhang, X Yang, N Ding, M Xiang, Q Zhu… - Frontiers in …, 2019 - frontiersin.org
Purpose: We conducted this study to determine the relationship between PD-1/PD-L1
inhibitors and the incidence risk of peripheral neuropathy in patients with solid tumors …

[图书][B] The Role of AMPK Activation in the Attenuation of Chronic Pain

K Inyang - 2019 - search.proquest.com
Chronic pain is a serious medical condition that impacts over 100 million Americans each
year. Metformin is a widely prescribed drug used in the treatment of type II diabetes that has …