Regulation of ribosome biogenesis in skeletal muscle hypertrophy
VC Figueiredo, JJ McCarthy - Physiology, 2019 - journals.physiology.org
The ribosome is the enzymatic macromolecular machine responsible for protein synthesis.
The rates of protein synthesis are primarily dependent on translational efficiency and …
The rates of protein synthesis are primarily dependent on translational efficiency and …
[HTML][HTML] The importance of resistance exercise training to combat neuromuscular aging
Older adults undergoing age-related decrements in muscle health can benefit substantially
from resistance exercise training, a potent stimulus for whole muscle and myofiber …
from resistance exercise training, a potent stimulus for whole muscle and myofiber …
Muscle fibre activation is unaffected by load and repetition duration when resistance exercise is performed to task failure
Key points Performing resistance exercise with heavier loads is often proposed to be
necessary for the recruitment of larger motor units and activation of type II muscle fibres …
necessary for the recruitment of larger motor units and activation of type II muscle fibres …
Testosterone therapy induces molecular programming augmenting physiological adaptations to resistance exercise in older men
N Gharahdaghi, S Rudrappa, MS Brook… - Journal of Cachexia …, 2019 - Wiley Online Library
Background The andropause is associated with declines in serum testosterone (T), loss of
muscle mass (sarcopenia), and frailty. Two major interventions purported to offset …
muscle mass (sarcopenia), and frailty. Two major interventions purported to offset …
Revisiting the roles of protein synthesis during skeletal muscle hypertrophy induced by exercise
VC Figueiredo - American Journal of Physiology …, 2019 - journals.physiology.org
Protein synthesis is deemed the underpinning mechanism enhancing protein balance
required for skeletal muscle hypertrophy in response to resistance exercise. The current …
required for skeletal muscle hypertrophy in response to resistance exercise. The current …
Muscle‐specific changes in protein synthesis with aging and reloading after disuse atrophy
Background Successful strategies to halt or reverse sarcopenia require a basic
understanding of the factors that cause muscle loss with age. Acute periods of muscle loss in …
understanding of the factors that cause muscle loss with age. Acute periods of muscle loss in …
[HTML][HTML] Molecular regulation of human skeletal muscle protein synthesis in response to exercise and nutrients: a compass for overcoming age-related anabolic …
Skeletal muscle mass, a strong predictor of longevity and health in humans, is determined
by the balance of two cellular processes, muscle protein synthesis (MPS) and muscle …
by the balance of two cellular processes, muscle protein synthesis (MPS) and muscle …
[HTML][HTML] Six weeks of low-load blood flow restricted and high-load resistance exercise training produce similar increases in cumulative myofibrillar protein synthesis …
P Sieljacks, J Wang, T Groennebaek, E Rindom… - Frontiers in …, 2019 - frontiersin.org
Purpose: High-load resistance exercise contributes to maintenance of muscle mass, muscle
protein quality, and contractile function by stimulation of muscle protein synthesis (MPS) …
protein quality, and contractile function by stimulation of muscle protein synthesis (MPS) …
Effect of blood flow restricted resistance exercise and remote ischemic conditioning on functional capacity and myocellular adaptations in patients with heart failure
T Groennebaek, P Sieljacks, R Nielsen… - Circulation: Heart …, 2019 - Am Heart Assoc
Background: Patients with congestive heart failure (CHF) have impaired functional capacity
and inferior quality of life. The clinical manifestations are associated with structural and …
and inferior quality of life. The clinical manifestations are associated with structural and …
It's not just about protein turnover: the role of ribosomal biogenesis and satellite cells in the regulation of skeletal muscle hypertrophy
Skeletal muscle has indispensable roles in regulating whole body health (eg glycemic
control, energy consumption) and, in being central in locomotion, is crucial in maintaining …
control, energy consumption) and, in being central in locomotion, is crucial in maintaining …