[HTML][HTML] Emerging roles of circRNA in formation and progression of cancer

Y Yin, J Long, Q He, Y Li, Y Liao, P He, W Zhu - Journal of Cancer, 2019 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs) are recently discovered as a special novel type of endogenous
noncoding RNAs (ncRNAs), which form a covalently closed continuous loop and are highly …

LncRNAs with miRNAs in regulation of gastric, liver, and colorectal cancers: updates in recent years

C Tam, JH Wong, SKW Tsui, T Zuo, TF Chan… - Applied microbiology and …, 2019 - Springer
Long noncoding RNA (lncRNA) is a kind of RNAi molecule composed of hundreds to
thousands of nucleotides. There are several major types of functional lncRNAs which …

m6A mRNA methylation initiated by METTL3 directly promotes YAP translation and increases YAP activity by regulating the MALAT1-miR-1914-3p-YAP axis to …

D Jin, J Guo, Y Wu, J Du, L Yang, X Wang, W Di… - Journal of hematology & …, 2019 - Springer
Background METTL3 is an RNA methyltransferase that mediates m 6 A modification and is
implicated in mRNA biogenesis, decay, and translation. However, the biomechanism …

Evaluation of deep learning in non-coding RNA classification

N Amin, A McGrath, YPP Chen - Nature Machine Intelligence, 2019 - nature.com
Non-coding (nc) RNA plays a vital role in biological processes and has been associated
with diseases such as cancer. Classification of ncRNAs is necessary for understanding the …

PTENP1/miR-20a/PTEN axis contributes to breast cancer progression by regulating PTEN via PI3K/AKT pathway

X Gao, T Qin, J Mao, J Zhang, S Fan, Y Lu… - Journal of Experimental …, 2019 - Springer
Background Long non-coding RNA PTENP1, the pseudogene of PTEN tumor suppressor,
has been reported to exert its tumor suppressive function via modulation of PTEN …

[HTML][HTML] The evolution of long noncoding RNA acceptance in prostate cancer initiation, progression, and its clinical utility in disease management

VR Ramnarine, M Kobelev, EA Gibb, M Nouri, D Lin… - European urology, 2019 - Elsevier
Context It is increasingly evident that non–protein-coding regions of the genome can give
rise to transcripts that form functional layers of the cancer genome. One of most abundant …

Long non-coding RNA in CNS injuries: a new target for therapeutic intervention

L Zhang, H Wang - Molecular Therapy-Nucleic Acids, 2019 - cell.com
CNS injuries, such as traumatic brain injury (TBI), subarachnoid hemorrhage (SAH),
intracerebral hemorrhage (ICH), and cerebral ischemic stroke, are important causes of death …

LncRNA PVT1 promotes proliferation and invasion through enhancing Smad3 expression by sponging miR-140-5p in cervical cancer

QQ Chang, CY Chen, Z Chen, S Chang - Radiology and Oncology, 2019 - sciendo.com
Background. Cervical cancer is one of the most frequent malignancies among females
worldwide. Increasing evidence have indicated the participation of long noncoding RNAs …

Methylation and transcriptome analysis reveal lung adenocarcinoma-specific diagnostic biomarkers

R Li, YE Yang, YH Yin, MY Zhang, H Li… - Journal of translational …, 2019 - Springer
Background DNA methylation can regulate the role of long noncoding RNAs (lncRNAs) in
the development of lung adenocarcinoma (LUAD). The present study aimed to identify …

LncRNA SBF2-AS1 promotes the progression of cervical cancer by regulating miR-361-5p/FOXM1 axis

F Gao, J Feng, H Yao, Y Li, J Xi… - … cells, nanomedicine, and …, 2019 - Taylor & Francis
Long non-coding RNAs (lncRNAs) have been identified as critical players in tumorigenesis.
Previous studies revealed that lncRNA SBF2-AS1 was involved in tumor progression …