[HTML][HTML] The coordination between B cell receptor signaling and the actin cytoskeleton during B cell activation

J Li, W Yin, Y Jing, D Kang, L Yang, J Cheng… - Frontiers in …, 2019 - frontiersin.org
B-cell activation plays a crucial part in the immune system and is initiated via interaction
between the B cell receptor (BCR) and specific antigens. In recent years with the help of …

Antigen receptor function in the context of the nanoscale organization of the B cell membrane

MR Gold, MG Reth - Annual review of immunology, 2019 - annualreviews.org
The B cell antigen receptor (BCR) plays a central role in the self/nonself selection of B
lymphocytes and in their activation by cognate antigen during the clonal selection process. It …

Membrane organization and physical regulation of lymphocyte antigen receptors: A biophysicist's perspective

L Limozin, PH Puech - The Journal of Membrane Biology, 2019 - Springer
Receptors at the membrane of immune cells are the central players of innate and adaptative
immunity, providing effective defence mechanisms against pathogens or cancer cells. Their …

Carbohydrate-dependent B cell activation by fucose-binding bacterial lectins

I Wilhelm, E Levit-Zerdoun, J Jakob, S Villringer… - Science …, 2019 - science.org
Bacterial lectins are typically multivalent and bind noncovalently to specific carbohydrates
on host tissues to facilitate bacterial adhesion. Here, we analyzed the effects of two fucose …

A symmetric geometry of transmembrane domains inside the B cell antigen receptor complex

C Gottwick, X He, A Hofmann… - Proceedings of the …, 2019 - National Acad Sciences
B lymphocytes have the ability to sense thousands of structurally different antigens and
produce cognate antibodies against these molecules. For this they carry on their surface …

[HTML][HTML] A new branched proximity hybridization assay for the quantification of nanoscale protein–protein proximity

S Zheng, M Sieder, M Mitterer, M Reth, M Cavallari… - Plos …, 2019 - journals.plos.org
Membrane proteins are organized in nanoscale compartments. Their reorganization plays a
crucial role in receptor activation and cell signaling. To monitor the organization and …

Investigating Ordered Phase-Like Domains on the Membrane of Intact B Cells Using Super-Resolution Microscopy

M Nunez - 2019 - deepblue.lib.umich.edu
B cells lymphocytes are responsible for mounting an immune response in a variety of
species. B cells are typically activated through the antigen-binding site of its B cell receptors …

Membrane domains and phosphatase exclusion produce robust signaling responses in B cells engaged with natural ligands and artificial cross-linkers presented on …

MF Núñez, K Wisser, SL Veatch - bioRxiv, 2019 - biorxiv.org
B cells respond to a wide variety of antigens with varying valiancy and mode of presentation
to the highly expressed B cell receptor (BCR). We previously demonstrated that clustering …

Vaccine molecules

R BRAATHEN, B Bogen - 2019 - Google Patents
Influenza A viruses circulate among human populations engender significant morbidity and
mortality. Most inactivated and live-attenuated vaccines against seasonal and pandemic …

Studies to Elucidate Host Immune Mechanisms Involved in the Blastocystis Sp. Subtype 3 Symptomatic and Asymptomatic Infection

S Sugadan - 2019 - search.proquest.com
Blastocystis sp. is an enteric protozoan parasite of humans and many animals. Blastocystis
sp. ST3 proves to be the highest frequency case in most populations around the world and it …