Glucocorticoids regulate fundamental processes of the human body and control cellular
functions such as cell metabolism, growth, differentiation, and apoptosis. Moreover …

Infiltration of memory CD4+ T cells in synovial joints of Rheumatoid Arthritis (RA) patients
has been reported since decades. Moreover, several genome wide association studies …

Tocilizumab (TCZ) is an interleukin-6 (IL-6) inhibitor used for the treatment of rheumatoid
arthritis (RA). It was developed in 2008, and its effectiveness is supported by evidence from …

Remission in rheumatoid arthritis: missing objectives by using inadequate DAS28 targets |
Nature Reviews Rheumatology Skip to main content Thank you for visiting nature.com. You are …

The neuroendocrine and immune systems are coordinated to maintain the homeostasis of
the organism, generating bidirectional communication through shared mediators and …

Rheumatoid arthritis is characterized by synovial proliferation, neovascularization and
leucocyte extravasation leading to joint destruction and functional disability. The blood …

Chronic inflammation is the underlying pathological condition that results in fibrotic
diseases. More recently, many forms of cancer have also been linked to chronic tissue …

Psoriatic arthritis (PsA) is an immune-mediated, systemic inflammatory disorder. PsA can
present with heterogeneous clinical features. Advances in understanding the …

Kirenol is a diterpenoid extracted from the Chinese herbal medicine Siegesbeckiae.
Siegesbeckiae has been used to treat Rheumatoid arthritis (RA) in China for several …

Periodontitis is an infectious disease characterized by chronic inflammation and progressive
destruction of periodontal tissues. Chronic inflammatory environment may affect …